Results 201 to 210 of about 86,752 (290)

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

open access: yesHepatology Research, Volume 56, Issue 4, Page 420-435, April 2026.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura   +11 more
wiley   +1 more source

Latent Intrarenal Renin-Angiotensin-Aldosterone System Activation Could Persist Until Early School-Aged in Children with a History of Low Birth Weight. [PDF]

open access: yesBiomark Insights
Ishimori S   +13 more
europepmc   +1 more source

Comorbidities and Healthcare Utilization in 4197 Patients With Prurigo Nodularis in Israel: A Cross‐Sectional Population‐Based Analysis

open access: yesInternational Journal of Dermatology, Volume 65, Issue 4, Page 763-773, April 2026.
ABSTRACT Background Prurigo nodularis patients face a significant burden of comorbidities, necessitating a comprehensive approach to care. We aimed to explore the association between prurigo nodularis, its comorbid conditions, and healthcare usage patterns.
Yuliya Valdman‐Grinshpoun   +4 more
wiley   +1 more source

Patient Characteristics and Clinical Outcomes in a Specialist Hypertension Clinic: A Pragmatic Real‐World Single‐Center Observational Study

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Patients referred to specialist hypertension clinics often have complex disease characterized by secondary causes, treatment resistance and coexisting kidney disease. Real‐world outcome data in this setting remain limited. We conducted a retrospective cohort study of 199 patients attending a tertiary hypertension clinic between January 2017 ...
William R. Marshall   +5 more
wiley   +1 more source

The urinary albumin‐to‐creatinine ratio can direct personalized prevention and treatment for cardiovascular and chronic kidney disease

open access: yesJournal of Internal Medicine, Volume 299, Issue 4, Page 444-466, April 2026.
Abstract Increased urinary albumin excretion is a strong predictor for cardiovascular events in persons with and without decreased glomerular filtration rate and can be assessed with the urinary albumin‐to‐creatinine ratio (UACR), which is a selective, sensitive, and convenient method for patients.
Holly J. Kramer, George L. Bakris
wiley   +1 more source

Renal Function and the Role of the Renin-Angiotensin-Aldosterone System (RAAS) in Normal Pregnancy and Pre-Eclampsia. [PDF]

open access: yesJ Clin Med
Tsikouras P   +16 more
europepmc   +1 more source

Role of atrial natriuretic factor, cyclic GMP and the renin-aldosterone-system in acute volume regulation of healthy human subjects [PDF]

open access: yes, 1988
Arendt, Rainer M.   +6 more
core   +1 more source

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