Results 241 to 250 of about 141,530 (342)

Modulation of the intracellular renin-angiotensin-aldosterone system of human mesangial cells submitted to aldosterone stimulus

, 2017
Danielle [UNIFESP] Stoll
openalex   +1 more source

SGLT2 inhibitor or metformin as standard treatment in early‐stage type 2 diabetes? Baseline data in SMARTEST, a novel, decentralised, register‐based randomised trial on prevention of diabetic complications

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1327-1338, February 2026.
Abstract Aims Metformin has hitherto not been proven superior to other type 2 diabetes (T2D) medications for the prevention of organ complications. The aim of this study is to report baseline data and blinded interim analyses in the register‐based randomised clinical trial (RRCT) SMARTEST, which compares metformin and the SGLT2 inhibitor dapagliflozin ...
Jan W. Eriksson, Giovanni Fanni, Martin H. Lundqvist, Stefan Jansson, Karin Rådholm, Sheyda Sofizadeh, Vagia Patsoukaki, Albert Nilsson, Daniel Lindholm, Olov Rolandsson, Anna Norhammar, Elisabet Granstam, Björn Eliasson, Louise Bennet, Johan Sundström   +14 more
wiley   +1 more source

Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload

, 2015
Elena Montes‐Cobos, Xiao Li, Henrike J. Fischer, André Sasse, Sebastian Kügler, Michael Didié, Karl Toischer, Martin Faßnacht, Ralf Dressel, Holger M. Reichardt   +9 more
openalex   +2 more sources

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

Journal of Diabetes Investigation, Volume 17, Issue 2, Page 197-204, February 2026.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

The Emerging Role of Aldosterone Synthase Inhibitors in Overcoming Renin-Angiotensin-Aldosterone System Therapy Limitations: A Narrative Review. [PDF]

Card Fail Rev
Patel SK, Teoh H, Saunthar A, Yau TM, Verma S.   +4 more
europepmc   +1 more source

Moderate to Severe Obstructive Sleep Apnea Is a Risk Factor for Severe COVID‐19—A Nationwide Cohort Study

Journal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT The impact of obstructive sleep apnea (OSA) and positive airway pressure (PAP) treatment on COVID‐19 severity is unclear. In this population‐based, nationwide study using multi‐register data, we aimed to assess if OSA is a risk factor for COVID‐19 severity and how adherence to PAP treatment and clinical characteristics affect the risk. Swedish
Mirjam Ljunggren, Andreas Palm, Magnus Ekström, Josefin Sundh, Ludger Grote, Huiqi Li, Fredrik Nyberg, Össur Ingi Emilsson   +7 more
wiley   +1 more source

Renin-Angiotensin-Aldosterone System Profiling in Horses Before and After Exercise. [PDF]

J Vet Intern Med
Holbrook T, Hernandez J, McCarrel T, Lester G, Sleeper M, Domenig O, Adin D.   +6 more
europepmc   +1 more source

Acquisition of renin-angiotensin-aldosterone system inhibitors for the treatment of cardiovascular diseases in regions of the Far Eastern Federal District

, 2020
М. С. Соболева, Е. Е. Лоскутова   +1 more
openalex   +2 more sources

Longer duration of loss of consciousness in older patients is related to Renin-Angiotensin-Aldosterone System dysfunction [PDF]

, 2013
Jacek Gajek, Dorota Zyśko
openalex   +1 more source

The renin-angiotensin-aldosterone system: a crossroad from arterial hypertension to heart failure

Heart Failure Reviews, 2019
N. Pugliese, S. Masi, S. Taddei
semanticscholar   +1 more source