Results 21 to 30 of about 141,530 (342)

The renin‐angiotensin‐aldosterone system, neurohumoral axis and cardiovascular mortality in LURIC

The Journal of Clinical Hypertension, 2022
Although neurohormones and Renin‐Angiotensin‐Aldosterone‐System (RAAS) components are important predictors of cardiovascular mortality (CVM), their importance for predicting outcomes in patients with/without RAAS‐blockers and different degrees of ...
Babak Yazdani, Graciela E. Delgado, Marcus E. Kleber, Gökhan Yücel, Faeq Husain‐Syed, Thomas D. Kraemer, Jan Jochims, Jan Leipe, Winfried März, Bernhard K. Krämer   +9 more
doaj   +1 more source

Regulation of the renin-angiotensin-aldosterone system by cyclic nucleotides and phosphodiesterases

Frontiers in Endocrinology, 2023
The renin-angiotensin-aldosterone system (RAAS) is one of the key players in the regulation of blood volume and blood pressure. Dysfunction of this system is connected with cardiovascular and renal diseases.
Stepan Gambaryan, Sanika Mohagaonkar, Sanika Mohagaonkar, Viacheslav O. Nikolaev, Viacheslav O. Nikolaev   +4 more
doaj   +1 more source

Renin–Angiotensin–Aldosterone System and Immunomodulation: A State-of-the-Art Review

Cells, 2021
The renin–angiotensin system (RAS) has long been described in the field of cardiovascular physiology as the main player in blood pressure homeostasis. However, other effects have since been described, and include proliferation, fibrosis, and inflammation.
D. Laghlam, Mathieu Jozwiak, L. Nguyen
semanticscholar   +1 more source

The Role of Renin-Angiotensin-Aldosterone System in the Heart and Lung: Focus on COVID-19

Frontiers in Pharmacology, 2021
The renin-angiotensin-aldosterone system (RAAS) firstly considered as a cardiovascular circulating hormonal system, it is now accepted as a local tissue system that works synergistically or independently with the circulating one.
A. Mascolo, C. Scavone, C. Rafaniello, A. De Angelis, K. Urbanek, Gabriella di Mauro, D. Cappetta, L. Berrino, F. Rossi, A. Capuano   +9 more
semanticscholar   +1 more source

Patiromer for the management of hyperkalaemia in patients receiving renin–angiotensin–aldosterone system inhibitors for heart failure: design and rationale of the DIAMOND trial

European Journal of Heart Failure, 2021
In patients with current or a history of hyperkalaemia, treatment with renin–angiotensin–aldosterone system inhibitors (RAASi) is often compromised. Patiromer, a novel potassium (K+) binder, may improve serum K+ levels and adherence to RAASi.
J. Butler, S. Anker, T. Siddiqi, A. Coats, F. Dorigotti, G. Filippatos, T. Friede, U. Göhring, M. Kosiborod, L. Lund, M. Metra, Carol Moreno Quinn, I. Piña, F. Pinto, P. Rossignol, P. Szecsödy, P. van der Meer, M. Weir, B. Pitt   +18 more
semanticscholar   +1 more source

Features of Neurohumoral Relations in Diastolic Dysfunction of the Heart in Adolescents with Myocardial Pathology

Zdorovʹe Rebenka, 2015
It is found that only in adolescents with I type left ventricular diastolic dysfunction, there is a significant activation of sympathoadrenal system, and in patients with type II and III, increasing activation of the renin-angiotensin-aldosterone system ...
L.F. Bohmat, V.V. Nikonovа, S.R. Tolmachevа, T.S. Vvedenskaia   +3 more
doaj   +1 more source

Renin-Angiotensin-Aldosterone System: From History to Practice of a Secular Topic. [PDF]

Int J Mol Sci
Renin–angiotensin–aldosterone system (RAAS) inhibitors are standard care in patients with hypertension, heart failure or chronic kidney disease (CKD). Although we have studied the RAAS for decades, there are still circumstances that remain unclear.
Ksiazek SH, Hu L, Andò S, Pirklbauer M, Säemann MD, Ruotolo C, Zaza G, La Manna G, De Nicola L, Mayer G, Provenzano M.   +10 more
europepmc   +2 more sources

Molecular Mechanisms Underlying Renin-Angiotensin-Aldosterone System Mediated Regulation of BK Channels

Frontiers in Physiology, 2017
Large-conductance calcium-activated potassium channels (BK channels) belong to a family of Ca2+-sensitive voltage-dependent potassium channels and play a vital role in various physiological activities in the human body.
Zhen-Ye Zhang, Ling-Ling Qian, Ru-Xing Wang   +2 more
doaj   +1 more source

Aldosterone status associates with insulin resistance in patients with heart failure-data from the ALOFT study [PDF]

, 2009
<b>Background</b>: Aldosterone plays a key role in the pathophysiology of heart failure. In around 50% of such patients, aldosterone 'escapes' from inhibition by drugs that interrupt the renin-angiotensin axis; such patients have a worse ...
Connell, J.M.C., Freel, E.M., Latini, R., Lewsey, J.D., Maggioni, A.P., McMurray, J.J.V., Pitt, B., Solomon, S., Tsorlalis, I.K.   +8 more
core   +1 more source

Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundDuring high sodium intake, the renin‐angiotensin‐aldosterone system is downregulated and nitric oxide signaling is upregulated in order to remain in sodium balance.
Kelly A. Hyndman, Elena V. Mironova, Jorge F. Giani, Courtney Dugas, Jessika Collins, Alicia A. McDonough, James D. Stockand, Jennifer S. Pollock   +7 more
doaj   +1 more source