Results 71 to 80 of about 174,628 (339)
The renin angiotensin aldosterone system
Pflügers Archiv - European Journal of PhysiologyAbstractIn this review, we will cover (i) the proteolytic cascade of the RAAS, (ii) its regulation by multiple feedback-controlled parameters, and (iii) the major effects of the RAAS. For the effects of the RAAS, we focus on the role of the RAAS in the regulation of volume homeostasis and vascular tone, as major determinants of arterial blood pressure.
Triebel, Hannah, Castrop, Hayo
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The renin-angiotensin system and malignancy [PDF]
Carcinogenesis, 2008 The renin-angiotensin system (RAS) is usually associated with its systemic action on cardiovascular homoeostasis. However, recent studies suggest that at a local tissue level, the RAS influences tumour growth. The potential of the RAS as a target for cancer treatment and the suggested underlying mechanisms of its paracrine effects are reviewed here ...
Jaclyn Neo +2 more
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Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]
, 2018 Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L +4 more
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Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Advanced Science, EarlyView.Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu +14 more
wiley +1 more source
Targeting the Renin–Angiotensin System
Hong Kong Journal of Nephrology, 2007 link_to_subscribed_fulltext
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Mechanism of development of pre-eclampsia linking breathing disorders to endothelial dysfunction [PDF]
, 2009 High blood pressure is an important component of pre-eclampsia. The underlying mechanism of development of hypertension in pre-eclampsia is complicated and still remains obscure.
Barnes, Vernon A. +2 more
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Advanced Science, EarlyView.The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong +12 more
wiley +1 more source
Blockade of the renin-angiotensin system [PDF]
, 2002 The renin-angiotensin-aldosterone system plays a key role in the regulation of fluid and electrolyte balance. Angiotensin-converting enzyme inhibitors inhibit angiotensin-converting enzyme and have been shown to be effective in many cardiovascular ...
Cheung, BMY
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AGING MEDICINE, EarlyView.A novel hypothesis: The disease of sympathetic overdrive (DSO) as a unifying mechanism for comorbidity in the elderly. ABSTRACT The coexistence of multimorbidity and geriatric syndromes is a big character and role target to manage for the clinic works in older age, but related theories still require innovation and exploration.
Li Jie, Kong Jian, Yu Boxin, Li Hongyang
wiley +1 more source
The renal renin-angiotensin system [PDF]
Advances in Physiology Education, 2009 The renin-angiotensin system (RAS) is a critical regulator of sodium balance, extracellular fluid volume, vascular resistance, and, ultimately, arterial blood pressure. In the kidney, angiotensin II exerts its effects to conserve salt and water through a combination of the hemodynamic control of renal blood flow and glomerular filtration rate and ...
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