Results 111 to 120 of about 217,588 (352)

Peripheral Blood Leukocyte Subpopulation Changes in Reaction to an Acute Psychosocial Stressor as Compared to an Active Placebo-Stressor in Healthy Young Males: Mediating Effects of Major Stress-Reactive Endocrine Parameters

Cells
Psychosocial stress has been proposed to induce a redistribution of immune cells, but a comparison with an active placebo-psychosocial stress control condition is lacking so far.
Lisa-Marie Walther, Angelina Gideon, Christine Sauter, Marcel Leist, Petra H. Wirtz   +4 more
doaj   +1 more source

Inhibition of renin and the (pro)renin receptor system

Blood Pressure, 2012
Renin is the rate-limiting step of the renin-angiotensin system (RAS) and can induce hypertension and cardiovascular diseases (CVDs) through the over-activated renin-angiotensin-converting enzyme (ACE)-angiotensin (Ang) II-Ang II type 1 receptor (AT(1)R) axis.
Robert D. Phillips, Franco Milani, Cuie Guang, Bo Jiang   +3 more
openaire   +3 more sources

Implementation of guideline‐directed medical therapy in patients with heart failure with reduced ejection fraction (OpTIMa‐HF Registry)

ESC Heart Failure, EarlyView.
Abstract Aims The last released European guidelines on the management of heart failure (HF) recommend in patients with chronic HF with reduced ejection fraction (HFrEF) a pharmacological approach based on four fundamental drugs to be rapidly implemented and then uptitrated to modify disease progression.
Stefania Paolillo, Christian Basile, Federica Marzano, Dario Bruzzese, Piergiuseppe Agostoni, Irene Mattavelli, Angelo Aloisio, Pietro Ameri, Martina Solimano, Natale Daniele Brunetti, Paolo Calabrò, Arturo Cesaro, Matteo Cameli, Giulia Elena Mandoli, Erberto Carluccio, Chiara Belardinelli, Stefano Carugo, Laura Casalino, Emilia Chiuini, Deborah Cosmi, Frank Lloyd Dini, Mariafrancesca Di Santo, Gennaro Esposito, Ferdinando Ferrara, Maria Francesca Fierro, Gennaro Galasso, Luca Gallo, Antonella Rispoli, Paola Gargiulo, Francesco Grigioni, Andrea Segreti, Franco Guarnaccia, Natale Guarnaccia, Federico Guerra, Emanuele Cicchirillo, Ciro Indolfi, Mauro Larcher, Adele Lillo, Marco Metra, Roberta Montisci, Maria Francesca Marchetti, Savina Nodari, Francesco Fioretti, Ermanno Nardi, Ugo Oliviero, Alberto Palazzuoli, Giuseppe Patti, Marco Pepe, Filomena Pacelli, Fabrizio Perrone Filardi, Giuseppe Putortì, Giosuè Santoro, Michele Senni, Emilia D'Elia, Paolo Severino, Andrea D'Amato, Simona Soriano, Gianfranco Sinagra, Maddalena Rossi, Monica Franzese, Giovanni Smaldone, Giovanni Battista Zito, Pasquale Perrone Filardi   +62 more
wiley   +1 more source

Trajectories in New York Heart Association functional class in heart failure across the ejection fraction spectrum: data from the Swedish Heart Failure Registry

European Journal of Heart Failure, Volume 24, Issue 11, Page 2093-2104, November 2022., 2022
Stable New York Heart Association (NYHA) class over time was much more frequent than an improvement or a worsening. Follow‐up NYHA class assessment, but not change in NYHA class over time, was independently associated with better prognosis. CI, confidence interval; HR, hazard ratio.
Felix Lindberg, Lars H. Lund, Lina Benson, Ulf Dahlström, Patric Karlström, Cecilia Linde, Giuseppe Rosano, Gianluigi Savarese   +7 more
wiley   +1 more source

Major Adverse Cardiovascular Events in Primary Aldosteronism After Adrenalectomy or Mineralocorticoid Receptor Antagonist Treatment: A Systematic Review and Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The object of this study was to investigate the incidence rate of major adverse cardiovascular event (MACE) among patients with primary aldosteronism (PA) after adrenalectomy or mineralocorticoid receptor antagonist (MRA) treatment.
Chien‐Wei Huang, Tse‐Ying Huang, Ya‐Fei Yang, Li‐Yang Chang, Yu‐Kang Tu, Vin‐Cent Wu, Jui‐Yi Chen   +6 more
doaj   +1 more source

Renin-Angiotensin System [PDF]

New England Journal of Medicine, 1975
ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire   +5 more sources

Investigation of left ventricular ejection fraction in a Swiss heart failure population: Insights into mortality and sex differences

ESC Heart Failure, EarlyView.
Graphical representation of main findings and article highlights. Abstract Aims Understanding heart failure (HF) characteristics is essential to improve patient outcomes. Categorizing HF beyond left ventricular ejection fraction (LVEF) is challenging due to heterogeneous clinical presentation and aetiologies.
Rubén Fuentes Artiles, Renald Meçani, Taulant Muka, Lukas Hunziker, Lukas Capék   +4 more
wiley   +1 more source

Renin‐angiotensin system revisited

Journal of Internal Medicine, 2008
New components and functions of the renin‐angiotensin system (RAS) are still being unravelled. The classical RAS as it looked in the middle 1970s consisted of circulating renin, acting on angiotensinogen to produce angiotensin I, which in turn was ...
F. Fyhrquist, O. Saijonmaa
semanticscholar   +1 more source

In heart failure, echocardiographic parameters of right ventricular function are powerful tools to predict renal failure

ESC Heart Failure, EarlyView.
Abstract Background Chronic kidney disease (CKD) has a high prevalence in patients with heart failure (HF) and is associated with prolonged hospitalization, increased need for intensive care and mortality. There is an urgent need to identify factors that influence the interaction between heart and kidney disorders, often described as cardiorenal ...
Alexander Reinecke, Paulina Dißmann, Norbert Frey, Oliver J. Müller, Hatim Seoudy, Johanne Frank, Derk Frank, Martina E. Spehlmann   +7 more
wiley   +1 more source

Association of Aldosterone, Renin, and Aldosterone to Renin Ratio with Metabolic Profile in Primary Aldosteronism

Diabetes, Metabolic Syndrome and Obesity
Minmin Han,1,2,* Xiaoming Cao,3,* Jian Zhang,1,2 Xifeng Yang,1,2 Yi Zhang,4,5 Yunfeng Liu1,2 1Department of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, 030000, People’s Republic of China; 2First Clinical Medical College ...
Han M, Cao X, Zhang J, Yang X, Zhang Y, Liu Y   +5 more
doaj