Results 11 to 20 of about 251,836 (347)
On the Specificity of Renin [PDF]
Science, 1940 Fil: Braun Menéndez, Eduardo. Instituto de Fisiología. Facultad de Medicina.
Fasciolo, Juan C. +3 more
openaire +4 more sources
Journal of the Renin-Angiotensin-Aldosterone System, 2005 Renin is an aspartic protease that consists of 2 homologous lobes. The cleft in between contains the active site with 2 catalytic aspartic residues.1 Unlike other aspartic proteases such as pepsin or cathepsin D, renin is monospecific and only cleaves angiotensinogen, to generate angiotensin (Ang) I.
Friedrich C. Luft +9 more
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Association of Elevated Serum Aldosterone Concentrations in Pregnancy with Hypertension
Biomedicines, 2023 Emerging evidence indicates a previously unrecognized, clinically relevant spectrum of abnormal aldosterone secretion associated with hypertension severity. It is not known whether excess aldosterone secretion contributes to hypertension during pregnancy.
Robin Shoemaker +10 more
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Autonomous Aldosterone Secretion in Patients with Adrenal Incidentaloma
Biomedicines, 2022 In recent years, research has emphasized the significance of mild clinical and biochemical presentations of primary aldosteronism (PA) that do not meet current diagnostic criteria of the syndrome.
Piotr Kmieć +4 more
doaj +1 more source
Variations in Arterial Blood Pressure after Kidney Transplantation [PDF]
, 1973 The course of hypertension within the first 2 months after kidney transplantation was correlated with renal function, plasma renin activity (PRA), and the daily maintenance dose of prednisone in 18 homograft recipients.
CORMAN, JACQUES L +7 more
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Kidney Renin Release under Hypoxia and Its Potential Link with Nitric Oxide: A Narrative Review
Biomedicines, 2023 The renin–angiotensin system (RAS) and hypoxia have a complex interaction: RAS is activated under hypoxia and activated RAS aggravates hypoxia in reverse.
Weiwei Kong +7 more
doaj +1 more source
Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells [PDF]
, 1990 In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated ...
Chegini, S. +3 more
core +1 more source
Immunohistochemical expression of intrarenal renin angiotensin system components in response to tempol in rats fed a high salt diet [PDF]
, 2017 AIM:To determine the effect of tempol in normal rats fed high salt on arterial pressure and the balance between antagonist components of the renal renin-angiotensin system.METHODS:Sprague-Dawley rats were fed with 8% NaCl high-salt (HS) or 0.4% NaCl ...
Cao, Gabriel Fernando +7 more
core +1 more source
Life, 2020 Components of the renin-angiotensin system (RAS) are expressed by cancer stem cells (CSCs) in many cancer types. We here investigated expression of the RAS by the CSC subpopulations in human head and neck metastatic malignant melanoma (HNmMM) tissue ...
Sam Siljee +7 more
doaj +1 more source
Pharmacological effects of raas blockade in ischemic nephropathy [PDF]
, 2016 Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio +8 more
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