Results 21 to 30 of about 217,588 (352)

Predicted Release and Analysis of Novel ACE-I, Renin, and DPP-IV Inhibitory Peptides from Common Oat (Avena sativa) Protein Hydrolysates Using in Silico Analysis

Foods, 2017
The renin-angiotensin-aldosterone system (RAAS) plays an important role in regulating hypertension by controlling vasoconstriction and intravascular fluid volume. RAAS itself is largely regulated by the actions of renin (EC 3.4.23.15) and the angiotensin-
Stephen Bleakley, Maria Hayes, Nora O’ Shea, Eimear Gallagher, Tomas Lafarga   +4 more
doaj   +1 more source

What’s new in the renin-angiotensin system?

Cellular and Molecular Life Sciences (CMLS), 2004
.Cellular entry of enveloped viruses is often dependent on attachment proteins expressed on the host cell surface. Viral envelope proteins bind these receptors, and, in an incompletely understood process, facilitate fusion of the cellular and viral ...
Wenhui Li, M. J. Moore, N. Vasilieva, J. Sui, S. Wong, M. Berne, M. Somasundaran, J. Sullivan, K. Luzuriaga, T. Greenough, H. Choe, M. Farzan   +11 more
semanticscholar   +1 more source

Primary Aldosteronism Screening Rates Differ with Sex, Race, and Comorbidities

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Primary aldosteronism (PA) is a common but under‐recognized cause of secondary hypertension. Data directly comparing screening rates across single and overlapping indications are lacking. Methods and Results We conducted a retrospective review
Adina F. Turcu, Winnie Nhan, Seda Grigoryan, Lei Zhang, Caitlin Urban, Haiping Liu, Lynn Holevinski, Lili Zhao   +7 more
doaj   +1 more source

Counter-regulatory renin–angiotensin system in cardiovascular disease

Nature Reviews Cardiology, 2019
The renin–angiotensin system is an important component of the cardiovascular system. Mounting evidence suggests that the metabolic products of angiotensin I and II — initially thought to be biologically inactive — have key roles in cardiovascular ...
María Paz Ocaranza, Jaime A Riquelme, Lorena García, J. Jalil, M. Chiong, R. Santos, S. Lavandero   +6 more
semanticscholar   +1 more source

The effect of medication on the aldosterone‐to‐renin ratio. A critical review of the literature

The Journal of Clinical Hypertension, 2021
The aldosterone‐to‐renin ratio (ARR) is a common screening test for primary aldosteronism in hypertensives. However, patients often use medications that could confound the ARR and, thereby, reduce the interpretability of the test.
Rawan M. Alnazer, Gregory P. Veldhuizen, Abraham A. Kroon, Peter W. deLeeuw   +3 more
doaj   +1 more source

Higher plasma renin activity is associated with increased kidney damage risk in patients with hypertension and glucose metabolic disorders

The Journal of Clinical Hypertension, 2022
The impact of renin on kidney remain unclear among hypertensives with glucose metabolic disorders (GMD). We aimed to evaluate the association between plasma renin activity (PRA) and kidney damage in hypertensive patients with GMD.
Mengyue Lin, Mulalibieke Heizhati, Lin Gan, Jing Hong, Ting Wu, Zuhere Xiamili, Ling Tong, Yue Lin, Nanfang Li   +8 more
doaj   +1 more source

Investigation of the impact of PTMs on the protein backbone conformation [PDF]

Amino Acids, Springer Verlag, 2019, 51 (7), pp.1065-1079, 2019
Post-Translational Modifications (PTMs) are known to play a critical role in the regulation of the protein functions. Their impact on protein structures, and their link to disorder regions have already been spotted on the past decade. Nonetheless, the high diversity of PTMs types, and the multiple schemes of protein modifications (multiple PTMs, of ...
arxiv   +1 more source

The renin‐angiotensin‐aldosterone system and its suppression

Journal of Veterinary Internal Medicine, 2019
Chronic activation of the renin‐angiotensin‐aldosterone system (RAAS) promotes and perpetuates the syndromes of congestive heart failure, systemic hypertension, and chronic kidney disease.
M. Ames, C. Atkins, B. Pitt
semanticscholar   +1 more source

Nicotine and the renin-angiotensin system.

American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2018
Cigarette smoking is the single most important risk factor for the development of cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has been in constant decline since the 1950s, the introduction of e-cigarettes or electronic ...
Joshua M. Oakes, Robert Fuchs, J. Gardner, E. Lazartigues, Xinping Yue   +4 more
semanticscholar   +1 more source

Renin, Renin Inhibition and Antihypertensive Therapy

Clinical and Experimental Hypertension. Part A: Theory and Practice, 1983
Research over the last 25 years established the renin-angiotensin-aldosterone system's important role in electrolyte and blood pressure homeostasis as well as in the pathophysiology of hypertension for which renin suppressive drugs, angiotensin antagonists and converting enzyme inhibitors provided selective pharmacological tools.
F. R. Bühler, Converting Enzyme Inhibitor   +1 more
openaire   +3 more sources