Results 21 to 30 of about 255,354 (220)

The evolutionary development of the renin angiotensin aldosterone system and its importance for the survival of the human species

open access: yesArterial Hypertension, 2021
Kidneys produce a number of substances that affect intrarenal blood circulation; however, the key system that regulates blood flow in both general and local circulation (including the renal circulation) is the renin-angiotensinaldosterone system (RAAS ...
Natalia Butt-Hussaim, Jacek Manitius
doaj   +1 more source

Cancer Stem Cells in Head and Neck Metastatic Malignant Melanoma Express Components of the Renin-Angiotensin System

open access: yesLife, 2020
Components of the renin-angiotensin system (RAS) are expressed by cancer stem cells (CSCs) in many cancer types. We here investigated expression of the RAS by the CSC subpopulations in human head and neck metastatic malignant melanoma (HNmMM) tissue ...
Sam Siljee   +7 more
doaj   +1 more source

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney [PDF]

open access: yes, 2015
BACKGROUND: The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal ...
A Hayes   +42 more
core   +2 more sources

RAS-challenge as a first-look test for detection of primary aldosteronism in patients with treatment-resistant hypertension

open access: yesBlood Pressure, 2023
Purpose Primary aldosteronism (PA), characterised by low-renin hypertension, confers a high cardiovascular risk and is the most common cause of secondary hypertension, with an increased prevalence in patients with treatment-resistant hypertension ...
Christian Beger   +6 more
doaj   +1 more source

Pharmacological effects of raas blockade in ischemic nephropathy [PDF]

open access: yes, 2016
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio   +8 more
core   +1 more source

Management of Patients with Adrenal Incidentalomas

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2014
The problem of choosing the tactics of the management of patients with adrenal incidentalomas is topical without doubt, considering the widespread use of modern instrumental methods for topical diagnosis.
L.А. Lutsenko
doaj   +1 more source

Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture [PDF]

open access: yes, 2015
Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in the management of cardiovascular diseases, there currently is no established ...
Fraga-Silva, Rodrigo   +2 more
core   +2 more sources

Personalized medicine—a modern approach for the diagnosis and management of hypertension [PDF]

open access: yes, 2017
The main goal of treating hypertension is to reduce blood pressure to physiological levels and thereby prevent risk of cardiovascular disease and hypertension-associated target organ damage.
Borghi, Claudio   +5 more
core   +1 more source

Changes in renal WT-1 expression preceding hypertension development [PDF]

open access: yes, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica   +8 more
core   +2 more sources

Mineralocorticoid hypertension

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
Hypertension affects about 10 - 25% of the population and is an important risk factor for cardiovascular and renal disease. The renin-angiotensin system is frequently implicated in the pathophysiology of hypertension, be it primary or secondary.
Vishal Gupta
doaj   +1 more source

Home - About - Disclaimer - Privacy