Results 71 to 80 of about 221,319 (346)

The renin-angiotensin system meets the hallmarks of cancer

Journal of the Renin-Angiotensin-Aldosterone System, 2015
The hallmarks of cancer are described as the distinctive and complementary capacities that cells must acquire during the multistep development of becoming a cancer cell that allow them to survive, proliferate and disseminate. The renin-angiotensin system
T. Wegman-Ostrosky, E. Soto-Reyes, S. Vidal-Millán, J. Śanchez-Corona   +3 more
semanticscholar   +1 more source

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

Renin lineage cells repopulate the glomerular mesangium after injury.

Journal of the American Society of Nephrology, 2015
Mesangial cell injury has a major role in many CKDs. Because renin-positive precursor cells give rise to mesangial cells during nephrogenesis, this study tested the hypothesis that the same phenomenon contributes to glomerular regeneration after murine ...
Charlotte Starke, H. Betz, Linda Hickmann, P. Lachmann, Björn Neubauer, J. Kopp, M. Sequeira-Lopez, R. A. Gomez, B. Hohenstein, V. Todorov, C. Hugo   +10 more
semanticscholar   +1 more source

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

British Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan, Katherine Z. Isoardi, Darren M. Roberts, Ong Sook Har   +3 more
wiley   +1 more source

The Renin-Angiotensin-Aldosterone System in Vascular Inflammation and Remodeling

International Journal of Inflammation, 2014
The RAAS through its physiological effectors plays a key role in promoting and maintaining inflammation. Inflammation is an important mechanism in the development and progression of CVD such as hypertension and atherosclerosis.
M. Pacurari, R. Kafoury, P. Tchounwou, K. Ndebele   +3 more
semanticscholar   +1 more source

Prescription drug use in breastfeeding mothers and infant exposure: A register‐based cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Breast milk is the optimal infant nutrition; however, many infants may be exposed to prescription drugs if used by their mothers during breastfeeding. The aim of this study was to evaluate the prevalence and patterns of prescription drug use among breastfeeding mothers and to assess the availability of relative infant dose information for
Ditte Resendal Gotfredsen, Ida M. Heerfordt, Christoffer Storm Baden, Henrik Horwitz, Christina Gade, Jon Trærup Andersen   +5 more
wiley   +1 more source

RENIN AND ALDOSTERONE PRODUCTION IN CHILDREN WITH HYDRONEPHROSIS WITH RELATION TO THE SEVERITY OF NON-DIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA AND TIME OF URINAL OBSTRUCTION ELIMINATION

Вопросы современной педиатрии, 2011
This article covers peculiarities of renin and aldosterone production in children with hydronephrosis with relation to the severity of non-differentiated connective tissue dysplasia (NDCTD) and time of urinal obstruction elimination. The grounds for this
A.M. Mambetova, R.A. Zhetichev, N.N. Shabalova, T.R. Indarokov   +3 more
doaj   +2 more sources

Remodeling of left ventricle in hypertensive patients with renal addition arteries: associations with renin level and glomerular filtration rate

Лечащий Врач, 2021
The article is devoted to analysis of relationship of left ventricular remodeling, plasma renin level, glomerular filtration rate in patients with arterial hypertension and renal additional arteries.
Yu. P. Red’ko, N. N. Gladkikh, A. V. Yagoda   +2 more
doaj  

The ratios of aldosterone / plasma renin activity (ARR) versus aldosterone / direct renin concentration (ADRR)

Journal of the Renin-Angiotensin-Aldosterone System, 2015
Primary aldosteronism (PA) is estimated to occur in 5–12% of patients with hypertension. Assessment of aldosterone / plasma renin activity (PRA) ratio (ARR) has been used as a screening test in patients suspected of PA. Direct determination of renin (DRC)
Piotr Glinicki, W. Jeske, L. Bednarek-Papierska, A. Kruszyńska, M. Gietka-Czernel, E. Rosłonowska, J. Słowińska-Srzednicka, A. Kasperlik-Załuska, W. Zgliczyński   +8 more
semanticscholar   +1 more source

The accessory renal arteries: A systematic review with meta‐analysis

Clinical Anatomy, EarlyView.
Abstract The accessory renal arteries (ARAs) are a well‐described variant of the renal vasculature with clinical implications for radiologists, surgeons, and clinicians. The aim of the present systematic review with meta‐analysis was to estimate the pooled prevalence of ARAs, including their variant number, origin, and termination, and to highlight ...
George Triantafyllou, Ioannis Paschopoulos, Andrzej Węgiel, Łukasz Olewnik, George Tsakotos, Nicol Zielinska, Maria Piagkou   +6 more
wiley   +1 more source