Results 51 to 60 of about 58,938 (145)

Development, evaluation and application of 3D QSAR Pharmacophore model in the discovery of potential human renin inhibitors

BMC Bioinformatics, 2011
Background Renin has become an attractive target in controlling hypertension because of the high specificity towards its only substrate, angiotensinogen.
John Shalini, Thangapandian Sundarapandian, Arooj Mahreen, Hong Jong, Kim Kwang, Lee Keun   +5 more
doaj   +1 more source

Renin and 1-year mortality in critically ill patients with ARDS: trajectories, discrimination, and survival analysis

Frontiers in Medicine
BackgroundWe investigated whether early and serial plasma renin concentration (PRC) is associated with 1-year mortality in critically ill patients with COVID-19-related acute respiratory distress syndrome (ARDS).MethodsWe conducted a single-center ...
Gabriele Melegari, Gabriele Melegari, Alessandro Belletti, Federica Arturi, Antonio Giansante, Arianna Gaspari, Fabio Gazzotti, Elisabetta Bertellini, Giovanni Landoni, Giovanni Landoni, Alberto Barbieri   +10 more
doaj   +1 more source

Emerging drug combinations to optimize renovascular protection and blood pressure goals

International Journal of Nephrology and Renovascular Disease, 2012
Carlos Escobar1, Rocio Echarri2, Vivencio Barrios31Department of Cardiology, Hospital Infanta Sofía, Madrid, Spain; 2Department of Nephrology, Hospital Infanta Sofía, Madrid, Spain; 3Department of Cardiology, Hospital Ramó
Escobar C, Echarri R, Barrios V
doaj  

Blood pressure lowering efficacy of renin inhibitors for primary hypertension. [PDF]

Cochrane Database Syst Rev, 2017
Musini VM, Lawrence KA, Fortin PM, Bassett K, Wright JM.   +4 more
europepmc   +1 more source

ACE inhibitors – angiotensin II receptor antagonists: A useful combination therapy for ischemic heart disease

Open Access Emergency Medicine, 2010
T S Mohamed Saleem1, K Bharani1, K Gauthaman21Department of Pharmacology, Annamacharya College of Pharmacy, Rajampet-516126, Kadapa Dist, Andhra Pradesh, India; 2Department of Drug Technology, Higher Institute of Medical Technology, Derna, LibyaAbstract:
T S Mohamed Saleem, K Bharani, K Gauthaman   +2 more
doaj  

Inhibition of RAS in diabetic nephropathy

International Journal of Nephrology and Renovascular Disease, 2015
Rabi Yacoub, Kirk N Campbell Department of Medicine, Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, USA Abstract: Diabetic kidney disease (DKD) is a progressive proteinuric renal disorder in patients with type 1 or type 2
Yacoub R, Campbell KN
doaj  

Renin inhibitors versus angiotensin receptor blockers for primary hypertension. [PDF]

Cochrane Database Syst Rev
Wang GM, Li LJ, Fan L, Xu M, Tang WL, Wright JM.   +5 more
europepmc   +1 more source

It's About Time: Potassium Risk With Combination Guideline-Directed Medical Therapy. [PDF]

Kidney Int Rep
Sinclair MR, Edmonston D.
europepmc   +1 more source

Targeting the renin-angiotensin system in sepsis-associated AKI: from pathophysiology to precision medicine. [PDF]

Front Immunol
Dong Y, Xia L, Shou S.
europepmc   +1 more source

Refractory hyponatremia secondary to idiopathic, isolated aldosterone deficiency. [PDF]

Oxf Med Case Reports
Free NW, Metropulos AE, Williams JR, Balasubramanian P, Principe DR.   +4 more
europepmc   +1 more source