Replication and trustworthiness [PDF]
Accountability in Research, 2021 This paper explores various relations that exist between replication and trustworthiness. After defining "trust", "trustworthiness", "replicability", "replication study", and "successful replication", we consider, respectively, how trustworthiness relates to each of the three main kinds of replication: reproductions, direct replications, and conceptual
Rik Peels, Lex Bouter
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Kinds of Replication: Examining the Meanings of “Conceptual Replication” and “Direct Replication” [PDF]
Perspectives on Psychological Science, 2022 Although psychology’s recent crisis has been attributed to various scientific practices, it has come to be called a “replication crisis,” prompting extensive appraisals of this putatively crucial scientific practice. These have yielded disagreements over what kind of replication is to be preferred and what phenomena are being explored, yet the ...
Maarten Derksen, Jill Morawski
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Identification of ORC1/CDC6-interacting factors in trypanosoma brucei reveals critical features of origin recognition complex architecture [PDF]
, 2012 DNA Replication initiates by formation of a pre-replication complex on sequences termed origins. In eukaryotes, the pre-replication complex is composed of the Origin Recognition Complex (ORC), Cdc6 and the MCM replicative helicase in conjunction with ...
Barry, J.D. +7 more
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Cohesin causes replicative DNA damage by trapping DNA topological stress [PDF]
, 2020 DNA topological stress inhibits DNA replication fork (RF) progression and contributes to DNA replication stress. In Saccharomyces cerevisiae, we demonstrate that centromeric DNA and the rDNA array are especially vulnerable to DNA topological stress ...
Baxter, Jonathan +2 more
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The mechanism of replication stalling and recovery within repetitive DNA
Nature Communications, 2022 DNA replication of repetitive sequences was recreated in a test tube using purified components. DNA alone was sufficient to induce stalling. Both stalling and recovery were dictated by the capacity of DNA to fold into unusual secondary structures.
Corella S. Casas-Delucchi +3 more
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Adaptation of HIV-1/HIV-2 Chimeras with Defects in Genome Packaging and Viral Replication
mBio, 2022 Frequent recombination is a hallmark of retrovirus replication. In rare cases, recombination occurs between distantly related retroviruses, generating novel viruses that may significantly impact viral evolution and public health.
Jonathan M. O. Rawson +10 more
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Archives of General Psychiatry, 2005 CONTEXT Little is known about lifetime prevalence or age of onset of DSM-IV disorders. OBJECTIVE To estimate lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the recently completed National Comorbidity Survey Replication ...
R. Kessler +5 more
semanticscholar +1 more source
Proficient replication of the yeast genome by a viral DNA polymerase [PDF]
, 2016 DNA replication in eukaryotic cells requires minimally three B-family DNA polymerases: Pol α, Pol δ, and Pol ϵ. Pol δ replicates and matures Okazaki fragments on the lagging strand of the replication fork.
Burgers, Peter M +2 more
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Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
mBio, 2021 Viral envelope glycoproteins are an important structural component on the surfaces of enveloped viruses that direct virus binding and entry and also serve as targets for the host adaptive immune response.
Cheng Man Lun +4 more
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A study on the correlation of nucleotide skews and the positioning of the origin of replication: different modes of replication in bacterial species [PDF]
, 2005 Deviations from Chargaff's 2nd parity rule, according to which A∼T and G∼C in single stranded DNA, have been associated with replication as well as with transcription in prokaryotes. Based on observations regarding mainly the transcription-replication co-
Almirantis, Yannis +1 more
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