Results 21 to 30 of about 3,159,718 (373)
Restriction of Influenza A Virus by SERINC5
mBio, 2022 Serine incorporator 5 (Ser5), a transmembrane protein, has recently been identified as a host antiviral factor against human immunodeficiency virus (HIV)-1 and gammaretroviruses like murine leukemia viruses (MLVs). It is counteracted by HIV-1 Nef and MLV
Kin Kui Lai +5 more
doaj +1 more source
Replication Study: Intestinal inflammation targets cancer-inducing activity of the microbiota
eLife, 2018 As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Eaton et al., 2015) that described how we intended to replicate selected experiments from the paper “Intestinal Inflammation Targets Cancer-Inducing Activity of the ...
B. Nixon +8 more
semanticscholar +1 more source
Distributional Replication [PDF]
Entropy, 2021 A function which transforms a continuous random variable such that it has a specified distribution is called a replicating function. We suppose that functions may be assigned a price, and study an optimization problem in which the cheapest approximation to a replicating function is sought.
openaire +5 more sources
Dicer prevents genome instability in response to replication stress [PDF]
, 2019 Dicer, an endoribonuclease best-known for its role in microRNA biogenesis and RNA interference pathway, has been shown to play a role in the DNA damage response and repair of double-stranded DNA breaks (DSBs) in mammalian cells.
Barra, Viviana +6 more
core +2 more sources
eLife, 2015 We have reconstituted a eukaryotic leading/lagging strand replisome comprising 31 distinct polypeptides. This study identifies a process unprecedented in bacterial replisomes.
Roxana E Georgescu +7 more
doaj +1 more source
Archives of General Psychiatry, 2005 BACKGROUND Little is known about the general population prevalence or severity of DSM-IV mental disorders. OBJECTIVE To estimate 12-month prevalence, severity, and comorbidity of DSM-IV anxiety, mood, impulse control, and substance disorders in the ...
R. Kessler +4 more
semanticscholar +1 more source
Replicability and replication in the humanities [PDF]
Research Integrity and Peer Review, 2019 A large number of scientists and several news platforms have, over the last few years, been speaking of a replication crisis in various academic disciplines, especially the biomedical and social sciences. This paper answers the novel question of whether we should also pursue replication in the humanities.
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Replicating replicability modeling of psychology papers [PDF]
Proceedings of the National Academy of Sciences, 2023 Youyou et al. (1) estimated the replicability of more than 14,000 psychology papers using a machine learning model, trained on main texts of 388 replicated studies. The authors identified mean replicability scores of psychological subfields. They also verified the causality of the model predictions; correlations between model predictions and study ...
Aske Mottelson, Dimosthenis Kontogiorgos
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Complexities associated with expression of Epstein-Barr virus (EBV) lytic origins of DNA replication. [PDF]
, 2007 EBV has two lytic origins (oriLyt) of DNA replication lying at divergent sites on the viral genome within a duplicated sequence (DS). The latter contains potential hairpin loops, ‘hinge’ elements and the promoters for transcripts from viral genes BHLF1 ...
Griffin, BE, Xue, SA
core +2 more sources
The consequences of replicating in the wrong orientation: Bacterial chromosome duplication without an active replication origin [PDF]
, 2015 Chromosome replication is regulated in all organisms at the assembly stage of the replication machinery at specific origins. In Escherichia coli the DnaA initiator protein regulates the assembly of replication forks at oriC.
Dimude, JU +8 more
core +1 more source