Results 11 to 20 of about 695,037 (266)
Cleavage of Dicer protein by I7 protease during vaccinia virus infection. [PDF]
PLoS ONE, 2015 Dicer is the key component in the miRNA pathway. Degradation of Dicer protein is facilitated during vaccinia virus (VV) infection. A C-terminal cleaved product of Dicer protein was detected in the presence of MG132 during VV infection.
Jhih-Si Chen +6 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2019 Bicyclol is a synthetic drug for hepatoprotection in clinic since 2004. Preliminary clinical observations suggest that bicyclol might be active against hepatitis C virus (HCV) with unknown mechanism.
Meng-Hao Huang +15 more
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c-Myc accelerates S-phase and requires WRN to avoid replication stress. [PDF]
PLoS ONE, 2009 c-Myc interacts with components of the pre-replication complex and directly regulates DNA replication [1]. However the consequences of this novel c-Myc function on cell cycle dynamics and replication-associated damage are unknown.
Kristin Robinson +3 more
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Virology Journal, 2019 Background Capsid (C) protein plays an important role in the replication of classical swine fever virus (CSFV). The ubiquitin proteasome system (UPS) involves in replication of many viruses via modulation of viral proteins.
Yuming Chen +8 more
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The V protein of canine distemper virus is required for virus replication in human epithelial cells. [PDF]
PLoS ONE, 2013 Canine distemper virus (CDV) becomes able to use human receptors through a single amino acid substitution in the H protein. In addition, CDV strains possessing an intact C protein replicate well in human epithelial H358 cells.
Noriyuki Otsuki +8 more
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Viruses, 2022 During viral evolution and adaptation, many viruses have utilized host cellular factors and machinery as their partners. HBx, as a multifunctional viral protein encoded by the hepatitis B virus (HBV), promotes HBV replication and greatly contributes to ...
Ah Ram Lee +3 more
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Pharmacological Inhibition of Protein Kinase C Reduces West Nile Virus Replication
Viruses, 2018 Flaviviruses are relevant animal and human pathogens that include West Nile virus (WNV), Japanese encephalitis virus, dengue virus, or Zika virus, among others. Currently, no licensed therapy is available to fight flaviviral infections. Protein kinases C
Ana B. Blázquez +3 more
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Inhibition of the HCV core protein on the immune response to HBV surface antigen and on HBV gene expression and replication in vivo. [PDF]
PLoS ONE, 2012 The hepatitis C virus (HCV) core protein is a multifunctional protein that can interfere with the induction of an immune response. It has been reported that the HCV core protein inhibits HBV replication in vitro.
Wenbo Zhu +8 more
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Molecular Systems Biology, 2010 The search for effective Hepatitis C antiviral therapies has recently focused on host sterol metabolism and protein prenylation pathways that indirectly affect viral replication. However, inhibition of the sterol pathway with statin drugs has not yielded
Christopher M Owens +7 more
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Viruses, 2020 The morphogenesis of Hepatitis B Virus (HBV) viral particles is nucleated by the oligomerization of HBc protein molecules, resulting in the formation of an icosahedral capsid shell containing the replication-competent nucleoprotein complex made of the ...
Hugues de Rocquigny +5 more
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