Results 181 to 190 of about 382,695 (354)

Inhibition of RNase to Attenuate Fungal‐Manipulated Rhizosphere Microbiome and Diseases

Advanced Science, EarlyView.
Fusarium graminearum uses its virulence effector Fg12, a fungal RNase, to manipulate the host rhizosphere microbiome and promote infection. Guanosine monophosphate (GMP) blocks Fg12's RNase activity. This reveals a key pathogen‐microbiota interaction mechanism and proposes GMP as a targeted strategy to disarm this core fungal effector, offering a ...
Bo Yang, Sen Yang, Xiaomi Wang, Yuanwei Zhang, Yao Zhao, Menghuan Tao, Jinyi Zhu, Wanxin Zhang, Yansu Wang, Kaixuan Duan, Yan Wang, Wenwu Ye, Zhenfei Guo, Yuanchao Wang   +13 more
wiley   +1 more source

Author Correction: Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation. [PDF]

Genome Biol
Kristof A, Karunakaran K, Allen C, Mizote P, Briggs S, Jian Z, Nash P, Blazeck J.   +7 more
europepmc   +1 more source

A Study on the Cell Layer Patterns of a Citrus Periclinal Chimera Reveals β‐Cryptoxanthin Regulation in Citrus Fruits

Advanced Science, EarlyView.
Researchers have identified a citrus chimera with distinctive tissue origins and carotenoid profiles. It is discovered that fruit tissues develop from all three cell layers but in different proportions. A key transcription factor, MYB107, regulates β‐cryptoxanthin production by directly activating carotenoid biosynthesis genes, explaining why some ...
Chi Zhang, Kaijie Zhu, Zhehui Zhang, Huiyu Ji, Qun Wu, Lin Zhang, Fuzhi Ke, Gang Wang, Min Zhang   +8 more
wiley   +1 more source

Tracking Copper sensing operon Repressor (CsoR) oligomerization in solution using Electron Paramagnetic Resonance spectroscopy. [PDF]

Protein Sci
Igbaria-Jaber Y, Mandato A, Hofmann L, Shenberger Y, Gevorkyan-Airapetov L, Sapir L, Saxena S, Ruthstein S.   +7 more
europepmc   +1 more source

The Amino-Acid Sequence of lac Repressor

, 1973
Konrad Beyreuther, Klaus Adler, Norbert Geisler, Alex Klemm   +3 more
openalex   +1 more source

Isolation of super-repressor mutants in the histidine utilization system of Salmonella typhimurium [PDF]

, 1975
David C. Hagen, S L Gerson, Boris Magasanik   +2 more
openalex   +1 more source

Discovery of a Potent and Selective TEAD Degrader with Durable Degradation Activity

Advanced Science, EarlyView.
KG‐FP‐003, a highly potent TEAD‐YAP PROTAC derived from the patented inhibitor is developed. It selectively degrades endogenous TEAD proteins in HiBiT systems without IMiD‐related off‐target effects. Screening across 867 cancer cell lines revealed broad and superior anti‐tumor activity, highlighting its therapeutic potential through targeted TEAD ...
Linhui Cao, Jing Yang, Yuhang Liu, Xiaotong Chen, Yufang Shi, Yunshuo Zhao, Yong Zhang, Jian Chen, Bowen Li, Wuqiang Wen, Lu Chen, Bo Peng, Lu Huang, Yanli Sun, Lixin Zhou, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Zhixiang Guo, Jing Xing, Guangya Zhu, Yazhou Wang, Baishan Jiang, Jing Lu, Kehao Zhao, Wenchao Lu   +25 more
wiley   +1 more source

Lead Aggravates Viral Disease and Represses the Antiviral Activity of Interferon Inducers

, 1974
J. H. Gainer
openalex   +2 more sources

Prophage Activation: An In Silico Platform for Identifying Prophage Regulatory Elements to Inform Phage Engineering Against Drug-Resistant Bacteria. [PDF]

Life (Basel)
Musrrat S, Han Z, Wang K, Huang Y, Xiang Y, Liu S, Yin W.   +6 more
europepmc   +1 more source

Control of Transcription of the Repressor Gene in Bacteriophage Lambda

, 1970
Stephen F. Heinemann, Willard G. Spiegelman   +1 more
openalex   +1 more source