Results 201 to 210 of about 382,695 (354)
Advanced Science, EarlyView.By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li +14 more
wiley +1 more source
Forced expression of MSR repeat transcripts above a threshold limit breaks heterochromatin organisation. [PDF]
Nat CommunChing RW +5 more
europepmc +1 more source
Kaiso is a genome-wide repressor of transcription that is essential for amphibian development [PDF]
, 2004 Dunican, Donncha S +6 more
core +1 more source
A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules
Advanced Science, EarlyView.Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang +6 more
wiley +1 more source
Proteolytic cleavage of bacteriophage lambda repressor in induction.
, 1975 Jeffrey W. Roberts, Charles W.M. Roberts
openalex +1 more source
Advanced Science, EarlyView.Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong +19 more
wiley +1 more source
A Tetracycline-Inducible Promoter Replacement System for <i>Schizosaccharomyces pombe</i>. [PDF]
MicroPubl BiolBashir S, Sivakumar S, Rhind N.
europepmc +1 more source