Results 211 to 220 of about 491,654 (394)

ZKSCAN3 is a master transcriptional repressor of autophagy.

Molecules and Cells, 2013
S. Chauhan, Jinesh G. Goodwin, Swati Chauhan, G. Manyam, Jing Wang, A. Kamat, D. Boyd   +6 more
semanticscholar   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Greening the Solid-Phase Peptide Synthesis of the First Bicyclic Analogue of the Arc Repressor and Its Binding to DNA. [PDF]

J Org Chem
Procino E, Bouzada D, D'Ingiullo S, Marinaccio L, Zhukov I, Stefanucci A, Mollica A.   +6 more
europepmc   +1 more source

GFI‑1 overexpression promotes cell proliferation and apoptosis resistance in mycosis fungoides by repressing Bax and P21

, 2021
Xiaoguang Gu, Yimeng Wang, Chunlei Zhang, Yongsheng Liu   +3 more
openalex   +2 more sources

Muscle Organoids Reveal Exercise‐Like Contractions Rapidly Promote Muscle Health Via Lamtor1's Signaling to Both AMPK and mTOR

Advanced Science, EarlyView.
This study develops a novel 3D human skeletal muscle organoid platform to study the immediate molecular effects of exercise‐like contractions. The model uncovers rapid proteomic and transcriptomic responses, resolving a fundamental paradox by demonstrating how exercise‐induced Lamtor1 coordinately activates both AMPK and mTORC1. Lamtor1 is a compelling
Ziyue Yao, Zongmin Jiang, Xupeng Liu, Liping Zhang, Siyu Guo, Yu Chen, Lanfang Luo, Shilin Ma, Peng Wang, Ng Shyh‐Chang   +9 more
wiley   +1 more source

An examination of the quinic acid utilization genes in Aspergillus niger reveals the involvement of 2 pH-dependent permeases. [PDF]

G3 (Bethesda)
Sgro M, Reid ID, Arentshorst M, Ram AFJ, Tsang A.   +4 more
europepmc   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source

Engineering wetware and software for the predictive design of compressed genetic circuits for higher-state decision-making. [PDF]

Nat Commun
Huang BD, Yu Y, Lee J, Repasky MW, Xie Y, Realff MJ, Wilson CJ.   +6 more
europepmc   +1 more source

Repressor [PDF]

, 2019
openaire   +1 more source

Proteolytic cleavage of the repressor (BlaI) of β-lactamase synthesis inStaphylococcus aureus [PDF]

, 1999
Richard A. Lewis, Stephen P. Curnock, K. G. H. Dyke   +2 more
openalex   +1 more source