Results 231 to 240 of about 382,695 (354)

Hypoxia‐Induced circPRELID2 Promotes Gastric Cancer Metastasis by Facilitating ZEB2 Translation via PCBP1 O‐GlcNAcylation

Advanced Science, EarlyView.
Under hypoxia, HIF1A is directly bound to the PRELID2 promoter to increase PRELID2 pre‐mRNA expression, followed by the DYRK1A–SFPQ–SAM68 complex binding to Alu‐containing introns in PRELID2 pre‐mRNA, leading to circPRELID2 circularization. CircPRELID2 interacts with PCBP1 and promotes its cytoplasmic retention.
Pengshan Zhang, Zai Luo, Yitian Xu, Yuan Zhang, Renchao Zhang, Nadina Paerhati, Shaopeng Zhang, Qianqian Cai, Zhengjun Qiu, Chen Huang   +9 more
wiley   +1 more source

Diastereoselective, Diversifiable Synthesis and Biological Evaluation of the Virginiamycin Inducers, the Virginiae Butanolides. [PDF]

Chembiochem
Castator KG, Frias-Gomez M, Wilbanks LE, Parkinson EI.   +3 more
europepmc   +1 more source

Kinetic studies of inducer binding to lactose repressor protein.

, 1976
Beth Friedman, John S. Olson, Kathleen S. Matthews   +2 more
openalex   +1 more source

Tead1a Initiates Transcriptional Priming Through the TEAD1a/YAP‐Notch1‐Spi1/Cebpα Axis to Promote Neutrophil Fate

Advanced Science, EarlyView.
This study discovered that the protein TEAD1a is crucial for neutrophil development. In zebrafish models, disrupting TEAD1a or its interaction with partner protein YAP1 caused severe neutrophil deficiency. TEAD1a functions during the early HSC stage, activates Notch1 signaling in the GMP stage, and triggers Spi1 and Cebpα to drive neutrophil terminal ...
Wang Yiqin, Yang Ruimeng, Wang Peihong, Liu Xiaohui, Yuan Hao, Huang Hongli, Zhou Yongjian, Xie Baoshu   +7 more
wiley   +1 more source

Complete Genome Sequences of Mycobacteriophages Balomoji, Crumble, Frederick, ShowerHandel, TinyTimmy and Zabiza. [PDF]

MicroPubl Biol
Middleton Z, Alves G, Bavuso E, Bui PA, Jandial K, Kirchner D, Kiskamp T, Morgan B, Osei K, Paradkar R, Taylor S, Johnson AA.   +11 more
europepmc   +1 more source

BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43

Advanced Science, EarlyView.
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan, Miao Han, Mengfei Zhang, Wenbo Chen, Fangde Xie, Xuan Luo, Wenping Wu, Congliang Wang, Donghui Yang, Bin Han, Haijing Zhu, Haisheng Yu, Na Li, Jinlian Hua   +13 more
wiley   +1 more source

Time-Course Gene Expression of '<i>Candidatus</i> Liberibacter solanacearum', Prophage, and <i>Wolbachia</i> Genes in <i>Bactericera cockerelli</i> from Ingestion to <i>in Planta</i> Transmission. [PDF]

Microorganisms
Saberi E, Qureshi JA, Brown JK.
europepmc   +1 more source

Molecular analysis of the DNA sequences involved in the transcriptional regulation of the phosphate-repressible acid phosphatase gene (PHO5) of Saccharomyces cerevisiae. [PDF]

, 1986
Lawrence W. Bergman, Diana Mcclinton, Stephen F. Madden, L. H. Preis   +3 more
openalex   +1 more source

PSMD14‐Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression

Advanced Science, EarlyView.
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu, Li‐Kun Ren, Xiao‐Bin Fei, Song‐Bai Liu, Yong‐Jia Gao, Jun‐Yi Hou, Chi Wang, Peng Liu, Chang‐Hao Zhu, Xing Wang, Yao‐Zhen Pan   +10 more
wiley   +1 more source

Antitoxin control of optimal transcriptional repression in the atypical HigB-HigA toxin-antitoxin system from Proteus vulgaris. [PDF]

Nucleic Acids Res
Pavelich IJ, Schureck MA, Srinivas P, Blackburn TM, Wang D, Hoffer ED, Boamah M, Zaldana K, Onuoha N, Miles SJ, Grabowicz M, Okafor CD, Dunham CM.   +12 more
europepmc   +1 more source