Results 241 to 250 of about 491,654 (394)

Dynamic patterns of gene expression match extracellular signals through push-pull regulation. [PDF]

PLoS Genet
Montano-Gutierrez LF, Sturrock M, Farquhar IL, Correia K, Shahrezaei V, Swain PS.   +5 more
europepmc   +1 more source

Expression analysis of aryl hydrocarbon receptor repressor (AHRR) gene in gallbladder cancer

, 2020
Puneet Kumar, Manoj Kumar Yadav, Khushi Verma, Ruhi Dixit, Juhi Singh, Satyendra K Tiwary, Gopeshwar Narayan, VK Dixit   +7 more
openalex   +1 more source

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi, Yu‐Ke Shen, Meng‐Yao Lv, Yu Sun, Yong‐Fang Lin, Zheng Wang, Xiao‐Liang Jie, Zheng Liu, Yang‐Tong Liu, Yang‐Xin Fu, Zhenhua Ren, Gui‐Zhen Wang, Guang‐Biao Zhou   +12 more
wiley   +1 more source

The cost of survival: mutation in a barley Strigolactone repressor HvD53A impairs photosynthesis but increases drought tolerance. [PDF]

Plant Cell Physiol
Korek M, Buchcik W, Chmielewska B, Daszkowska-Golec A, Fontana IM, Melzer M, Hensel G, Kumlehn J, Brewer PB, Uhrig GR, Marzec M.   +10 more
europepmc   +1 more source

Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties.

Immunity, 2009
R. Rutishauser, G. Martins, S. Kalachikov, A. Chandele, I. Parish, E. Meffre, Joshy Jacob, K. Calame, S. Kaech   +8 more
semanticscholar   +1 more source

U‐Shaped Response of Flowering Time to Low and High Nitrogen via a Transcription Feedback Loop in Rice

Advanced Science, EarlyView.
The “seesaw effect” of Nhd1‐Ghd7 module in regulating flowering time (days to heading in rice) responses to nitrogen (N) via Hd3a/RFT1: deficient‐N (DN) delays flowering via Ghd7‐mediated suppression of Nhd1; moderate‐N (MN) impairs this suppression, enhancing Nhd1 to promote flowering; whereas superior‐N (SN) delays flowering by Nhd1‐activated ...
Shunan Zhang, Guanzhong Shou, Xianping Li, Xuemin Song, Xuesong Li, Junjie Guo, Jiaqiang Lu, Yi Jin, Hongye Qu, Ming Yan, Wona Ding, Ying Liu, Guohua Xu   +12 more
wiley   +1 more source

Prophage Activation: An In Silico Platform for Identifying Prophage Regulatory Elements to Inform Phage Engineering Against Drug-Resistant Bacteria. [PDF]

Life (Basel)
Musrrat S, Han Z, Wang K, Huang Y, Xiang Y, Liu S, Yin W.   +6 more
europepmc   +1 more source

Efficient and exclusive induction of Tet repressor by the oligopeptide Tip results from co-variation of their interaction site [PDF]

, 2007
Marcus Klotzsche, Dagmar F. Goeke, Christian Berens, Wolfgang Hillen   +3 more
openalex   +1 more source

APETALA2 negatively regulates multiple floral organ identity genes in Arabidopsis by recruiting the co-repressor TOPLESS and the histone deacetylase HDA19

Development, 2012
N. Krogan, K. Hogan, J. Long
semanticscholar   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source