Results 241 to 250 of about 334,121 (353)

Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis. [PDF]

Nat Genet
Lim B, Kamal A, Gomez Ramos B, Adrian Segarra JM, Ibarra IL, Dignas L, Kindinger T, Volz K, Rahbari M, Rahbari N, Poisel E, Kafetzopoulou K, Böse L, Breinig M, Heide D, Gallage S, Barragan Avila JE, Wiethoff H, Berest I, Schnabellehner S, Schneider M, Becker J, Helm D, Grimm D, Mäkinen T, Tschaharganeh DF, Heikenwalder M, Zaugg JB, Mall M.   +28 more
europepmc   +1 more source

The v-mos and H-ras oncogene expression represses glucocorticoid hormone-dependent transcription from the mouse mammary tumor virus LTR. [PDF]

, 1986
Rolf Jaggi, Brian Salmons, Daniel B. Muellener, Bernd Groner   +3 more
openalex   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

Engineered Exosomes Carrying Super-Repressor IκB Reduced Biliary Atresia-Induced Liver Fibrosis in Minipig and Mouse Models. [PDF]

Pharmaceutics
Kang J, Park C, Yun H, Choi C, Seo W.
europepmc   +1 more source

Construction of an E. coli strain overproducing the Tn10-encoded TET repressor and its use for large scale purification. [PDF]

, 1984
R. Oehmichen, Gerd Klöck, Lothar Altschmied, Wolfgang Hillen   +3 more
openalex   +1 more source

Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

Advanced Science, EarlyView.
MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi, Yu Tian, Yu‐fan Wang, Yi‐ran Zhang, Ying Yin, Qing Tian, Lei Li, Bing‐xin Ma, Ximiao He, Li‐quan Zhou   +9 more
wiley   +1 more source

Repressor elements provide insights into tissue development and phenotypes in pigs. [PDF]

Zool Res
Zhang YD, Guo C, Liu H, Gao Y, Tan Y, Niu L, Wang L, Wang L, Irwin DM, Hou C, Zhou ZY, Zhang YP.   +11 more
europepmc   +1 more source

The Amino-Acid Sequence of lac Repressor

, 1973
Konrad Beyreuther, Klaus Adler, Norbert Geisler, Alex Klemm   +3 more
openalex   +1 more source

M6A Modified miR‐31‐5p Suppresses M1 Macrophage Polarization and Autoimmune Dry Eye by Targeting P2RX7

Advanced Science, EarlyView.
The upregulation of FTO in autoimmune dry eye suppresses the recognition of pri‐miR‐31 by DGCR8, thereby inhibiting the maturation of miR‐31‐5p and reducing its inhibitory effect on the target gene P2RX7. The activation of P2RX7 subsequently triggers the p38 MAPK signaling pathway and increases the level of M1‐related genes, thus exacerbating the ...
Lu Zhao, Xuejia Li, Min Gao, Lin Liu, Binyun Ma, Xun Liu, Jiachen Zhang, Ruoxuan Liu, Bei Du, Ruihua Wei, Hong Nian   +10 more
wiley   +1 more source

Two coacting shadow enhancers regulate twin of eyeless expression during early Drosophila development. [PDF]

Genetics
Dresch JM, Nourie LL, Conrad RD, Carlson LT, Tchantouridze EI, Tesfaye B, Verhagen E, Gupta M, Borges-Rivera D, Drewell RA.   +9 more
europepmc   +1 more source