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ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu+3 more
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Coordinated regulation of chemotaxis and resistance to copper by CsoR in <i>Pseudomonas putida</i>. [PDF]
He M+8 more
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OsBBX2 Delays Flowering by Repressing Hd3a Expression Under Long-Day Conditions in Rice. [PDF]
Yang Y+5 more
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A cross-species inducible system for enhanced protein expression and multiplexed metabolic pathway fine-tuning in bacteria. [PDF]
Li Y+8 more
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SAP30 promotes clear cell renal cell carcinoma proliferation and inhibits apoptosis through the MT1G axis. [PDF]
Guo W+6 more
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Regulatory Components for Bacterial Cell-Free Systems Engineering. [PDF]
Lee PW, Maerkl SJ.
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TAZ interactome analysis using nanotrap-based affinity purification-mass spectrometry.
Kelebeev J+3 more
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The retinoblastoma protein as a transcriptional repressor
Trends in Cell Biology, 1993The retinoblastoma protein (pRB) is one of the best-studied tumour suppressor gene products. Its loss during the genesis of many human tumours, its inactivation by several DNA tumour virus oncoproteins, and its ability to inhibit cell growth when introduced into dividing cells all suggest that pRB negatively regulates some aspect of normal cell growth.
Helin, K, Ed, H
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Bacteriophage Coat Protein as Repressor
Nature, 1968It seems that viral coat protein acts as a repressor of protein synthesis at the level of transcription rather than translation.
Robert E. Webster+2 more
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Modelling repressor proteins docking to DNA
Proteins: Structure, Function, and Genetics, 1998The docking of repressor proteins to DNA starting from the unbound protein and model-built DNA coordinates is modeled computationally. The approach was evaluated on eight repressor/DNA complexes that employed different modes for protein/ DNA recognition.
Michael J.E. Sternberg+5 more
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