Results 271 to 280 of about 1,854,175 (305)

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

Advanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan, Erdi Zhang, Yuwen Ma, Zirui Meng, Sisi Li, Yimeng Ren, Xiaohe Tian, Yangyi He, Giuseppe Battaglia, Dong Zhou, Yun Liao, Binwu Ying, Jinmei Li, Minjin Wang   +13 more
wiley   +1 more source

The root-knot nematode effector Mi1D08B targets a NINJA-family co-repressor to suppress jasmonate production and promote infection in soybean. [PDF]

Plant J
Li P, Zadegan SB, Coffey N, Ghosh N, Rice JH, El-Messidi A, Boshnag M, Islam T, Burch-Smith T, Pantalone V, Hewezi T.   +10 more
europepmc   +1 more source

RNA binding protein RBM20 regulates turtle temperature-dependent sex determination by repressing the splicing of Wt1 KTS

Wei Sun, Hongzhe Yang, Hang-Bo Hui, Jingzhi Bai, Fang Yan, Xinyi Wang, Qiran Chen, Zongji Wang, Chutian Ge   +8 more
openalex   +1 more source

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

PA5201 represses type III secretion system by binding to the P<i>_exsC</i> promoter in <i>Pseudomonas aeruginosa</i>. [PDF]

Microbiol Spectr
Wang L, Shen C, Yin L, Zhang Y, Zhang L, Liu S, Cheng Z, Wu W, Ha U-H, Jin S, Jin Y.   +10 more
europepmc   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Plasmid replication initiator protein TrfA represses the host type III secretion system in Pseudomonas aeruginosa

Yu Zhang, Liwen Yin, Qi Liu, Lepeng Wang, Chenyu Shen, Yifan Bian, Zhenzhen Ma, Un‐Hwan Ha, Zhihui Cheng, Weihui Wu, Shouguang Jin, Yongxin Jin   +11 more
openalex   +1 more source

CDK8 phosphorylation of DELLA limits Mediator recruitment in gibberellin signaling. [PDF]

Proc Natl Acad Sci U S A
Huang X, Chen H, Reser L, Reyes AV, Xu SL, Shabanowitz J, Hunt DF, Sun TP.   +7 more
europepmc   +1 more source

Research Advances on the Functions of Transcriptional Regulators in Filamentous Fungi. [PDF]

Microorganisms
Su J, Lin X, Xia Y, Zhao J, Chen Y, Wang D, Xue X.   +6 more
europepmc   +1 more source

Beyond light signaling: the broad regulatory spectrum of AFPs in plant growth and development. [PDF]

Front Plant Sci
Wang Q, Yuan J, Zhang Y, Yang B, Lin F.
europepmc   +1 more source