Results 271 to 280 of about 290,663 (301)

Lac repressor is a transient gene-activating protein

Cell, 1987
We show, using a combination of methods, that contrary to the usual view, lac repressor increases, by more than 100-fold, the initial binding of RNA polymerase to E. coli lac UV5 promoter DNA. Kinetic studies revealed that the repressor acts to block the isomerization step in transcription initiation.
S B, Straney, D M, Crothers
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Trp repressor protein controls its own structural gene

Journal of Molecular Biology, 1981
Abstract To study the regulation of expression of the trpR gene of Escherichia coli , fused transcriptional units consisting of the promoter-operator region of trpR and a functional but promoterless lacZ gene were constructed by techniques of cleavage and ligation in vitro .
G, Bogosian, K, Bertrand, R, Somerville
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Lactose repressor protein reaction with 2-chloromercuri-4-nitrophenol

Journal of Molecular Biology, 1976
Abstract Reaction of the lactose repressor protein with 2-chloromercuri-4-nitrophenol resulted in modification of two of the three cysteine residues per monomer at all pH values tested. At pH 8.1 it was possible to detect two equivalence points, corresponding to one and two mercurinitrophenol residues introduced per monomer.
D S, Yang, K S, Matthews
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Leukemia fusion proteins and co‐repressor complexes: Changing paradigms

Journal of Cellular Biochemistry, 2005
AbstractMany cases of acute myelogenous leukemia (AML) are characterized by non‐random chromosomal translocations that fuse a DNA‐binding protein with a transcriptional regulator, which in turn may aberrantly recruit a co‐repressor complex. The similarities in this pattern between different AML chimeric fusions have led to a paradigm that stresses the ...
Robert L, Redner, Johnson M, Liu
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Modification of tyrosine residues of the lactose repressor protein

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1977
Reaction of the lactose repressor protein from Escherichia coli with high molar excesses (up to 800 fold) of tetranitromethane resulted in modification of tyrosine residues in the amino-terminal and core regions of the molecule. Tyrosines 7 and 17 exhibit significant reactivity at low levels (5-10 fold molar excess) of tetranitromethane.
M E, Alexander, A A, Burgum, R A, Noall, M D, Shaw, K S, Matthews   +4 more
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The Trp Repressor, A Ligand-Activated Regulatory Protein

1992
Publisher Summary This chapter discusses the role of Trp repressor as a ligand-activated regulatory protein. The Trp repressor (protein) of Escherichia coli is one of the most exhaustively studied DNA-binding regulatory macromolecules. Its physiological role is to reduce or eliminate transcription from certain regulatable promoters through the ...
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Molecular Characterization of the VIP Receptor Transcriptional Repressor Protein

Annals of the New York Academy of Sciences, 2000
Abstract: The rat type 1 VIP receptor transcriptional repressor protein (VIPR‐RP) is a recently isolated novel transcription factor. In the study reported here, the functional domains of VIPR‐RP were characterized. To map the DNA binding domain, various regions of VIPR‐RP were either transcribed and translated in vitro or expressed in and purified ...
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Capsid protein of f2 as translational repressor

Biochemical and Biophysical Research Communications, 1967
R, Ward, K, Shive, R, Valentine
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Repressor Protein

2011
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Translation Repressor Proteins

2008
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