Results 141 to 150 of about 86,878,094 (191)
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Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2006
Resistance to thyroid hormone (RTH) is a rare autosomal dominant inherited syndrome of reduced end-organ responsiveness to thyroid hormone. Patients with RTH have elevated serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations and normal or slightly elevated serum thyroid stimulating hormone (TSH) level.
Tolulope O, Olateju +1 more
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Resistance to thyroid hormone (RTH) is a rare autosomal dominant inherited syndrome of reduced end-organ responsiveness to thyroid hormone. Patients with RTH have elevated serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations and normal or slightly elevated serum thyroid stimulating hormone (TSH) level.
Tolulope O, Olateju +1 more
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Reviews in Endocrine and Metabolic Disorders, 2000
The syndromes of resistance to thyroid hormone (RTH) are generally characterized by reduced tissue responsiveness to thyroid hormone (TH) despite elevated circulating levels of free T 3 and/or T 4 (Refetoff et al., 1993). It is associated with an inappropriately normal or raised serum TSH characteristic of impaired thyrotroph sensitivity.
R E, Weiss, S, Refetoff
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The syndromes of resistance to thyroid hormone (RTH) are generally characterized by reduced tissue responsiveness to thyroid hormone (TH) despite elevated circulating levels of free T 3 and/or T 4 (Refetoff et al., 1993). It is associated with an inappropriately normal or raised serum TSH characteristic of impaired thyrotroph sensitivity.
R E, Weiss, S, Refetoff
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Resistance to Thyroid Hormone in Pregnancy
Obstetrics & Gynecology, 2008Resistance to thyroid hormone manifests as high serum levels of free thyroxine and free triiodothyronine, with nonsuppressed thyroid stimulating hormone (TSH) levels. We report a case series of three patients with this condition, the changes in thyroid function tests during their pregnancies, and their obstetric outcome.Three pregnant women with ...
Simi, Dhingra +3 more
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Pituitary Resistance to Thyroid Hormones
Hormone Research, 2008Pituitary thyroid hormone resistance (PRTH) refers to a particular form of thyroid hormone refractoriness that is accompanied by peripheral hyperthyroidism, as only the TSH-secreting pituitary cells appear to be resistant to the effects of thyroid hormones. The presence of PRTH is suspected and diagnosed on the basis of the finding of high free thyroid
P, Beck-Peccoz +6 more
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Familial thyroid hormone resistance
The American Journal of Medicine, 1981Eight patients with thyroid hormone resistance were found in four generations of a kindred containing 19 members. Results of studies in this family are consistent with an autosomal dominant mode of inheritance for this disorder. The affected family members were clinically euthyroid but all had goiters and markedly increased serum thyroid hormone levels:
M H, Brooks +5 more
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Clinica Chimica Acta, 2005 Background: Thyroid hormones govern a wide range of metabolic processes in the body via thyroid hormone receptors (TR). We report a patient with mild resistance to thyroid hormone who was initially misdiagnosed and treated as having thyrotoxicosis ...
Sui-Fan Tong +2 more
exaly +2 more sources
Thyroid Hormone Generalized Resistance
Hormone Research, 2008The syndromes of thyroid hormone resistance may affect overall or only some tissues. The generalized resistance is an inherited disease which involves a familial eumetabolic or hypometabolic goiter, increased free thyroid hormones with normal or elevated plasma TSH levels; children may present mental retardation, deafness, short stature and delayed ...
C, Jaffiol +3 more
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2014
Resistance to thyroid hormone (RTH) or thyroid hormone action defect (THAD) is the most frequent form of syndromes of reduced sensitivity to thyroid hormone. It is characterized by variable tissue hyposensitivity to thyroid hormone. RTHβ (formerly only RTH) is caused by mutations in the thyroid hormone receptor β gene (THRB).
Kazumichi, Onigata, Gabor, Szinnai
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Resistance to thyroid hormone (RTH) or thyroid hormone action defect (THAD) is the most frequent form of syndromes of reduced sensitivity to thyroid hormone. It is characterized by variable tissue hyposensitivity to thyroid hormone. RTHβ (formerly only RTH) is caused by mutations in the thyroid hormone receptor β gene (THRB).
Kazumichi, Onigata, Gabor, Szinnai
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Familial thyroid hormone resistance
Metabolism, 1982Three phenotypically normal family members were discovered to have elevated thyroid function (T4, free T4, T3, 123I uptake), but were clinically euthyroid. Further evaluation of pituitary and peripheral indices of thyroid hormone action was consistent with the diagnosis of peripheral resistance to thyroid hormone.
D S, Cooper +5 more
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Thyroid hormone resistance syndromes
The American Journal of Medicine, 1993The thyroid hormone resistance syndromes are disorders in which the body's tissues are resistant to the effects of thyroid hormone. Generalized resistance to thyroid hormone (GRTH) is characterized by resistance in the pituitary gland and in most or all of the peripheral tissues.
M T, McDermott, E C, Ridgway
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