Results 151 to 160 of about 90,318,030 (246)

Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes

British Journal of Pharmacology, EarlyView.
Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
wiley   +1 more source

Characteristics of Dyslipidemia in Adults With Resistance to Thyroid Hormone β. [PDF]

Endocr Pract
Davis TME, Davis WA, Moran C, Lyons G, Bryden E, Chatterjee K.   +5 more
europepmc   +1 more source

Autoantibodies to selenoprotein P in chronic fatigue syndrome suggest selenium transport impairment and acquired resistance to thyroid hormone. [PDF]

Redox Biol, 2023
Sun Q, Oltra E, Dijck-Brouwer DAJ, Chillon TS, Seemann P, Asaad S, Demircan K, Espejo-Oltra JA, Sánchez-Fito T, Martín-Martínez E, Minich WB, Muskiet FAJ, Schomburg L.   +12 more
europepmc   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Editorial: Genetics of thyroid gland

Frontiers in Genetics, 2023
Tatijana Zemunik, Mirjana Babić Leko, Ivana Gunjača   +2 more
doaj   +1 more source

Resistance to Thyroid Hormone Due to a Missense Heterozygous Mutation in the <i>THR-β</i> Gene: A Challenging Diagnosis. [PDF]

AACE Endocrinol Diabetes
Vargas VM, Dwivedi S, Penquite SA.
europepmc   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Resistance to thyroid hormone in a child with thyroid agenesis: A case report with review of the literature. [PDF]

Ann Med Surg (Lond), 2022
Hasan KM, Mohammed BA, Ahmed SF, Ali RM, Abdulla BA, Tahir SH, Kakamad FH, Salih AM.   +7 more
europepmc   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Resistance to thyroid hormone due to a novel mutation in the thyroid beta receptor (THRβ) gene coexisting with autoimmune thyroid disease-A case report. [PDF]

Front Genet, 2023
Skowrońska-Jóźwiak E, Gach A, Cyniak-Magierska A, Nykel A, Jurkowska M, Lewiński A.   +5 more
europepmc   +1 more source