Results 21 to 30 of about 12,671 (210)

Effects of individualized resistance training prescription with heart rate variability on muscle strength, muscle size and functional performance in older women

open access: yesFrontiers in Physiology
IntroductionThis study aimed to investigate whether individualizing autonomic recovery periods between resistance training (RT) sessions (IND) using heart rate variability (HRV), measured by the root mean square of successive R-R interval differences ...
Diego Bittencourt   +8 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Within-individual design for assessing true individual responses in resistance training-induced muscle hypertrophy

open access: yesFrontiers in Sports and Active Living
Understanding interindividual variability in muscle hypertrophy in response to resistance training (RT) is a key focus of contemporary research. Common aims include identifying determinants of variability and recognizing individuals who do not respond to
Talisson Santos Chaves   +3 more
doaj   +1 more source

Older adults, clinicians, and researchers’ preferences for measuring adherence to resistance and balance exercises

open access: yesBMC Geriatrics, 2023
Background Resistance and balance training are important exercise interventions for older populations living with chronic diseases. Accurately measuring if an individual is adhering to exercises as prescribed is important to determine if lack of ...
Caitlin McArthur   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

In vitro activity of robenidine analogue NCL195 against methicillin-resistant Staphylococcus pseudintermedius

open access: yesMicrobiology Spectrum
The rise of difficult-to-treat infections among companion animals, particularly the increasing incidence of methicillin-resistant Staphylococcus pseudintermedius (MRSP) in dogs poses significant challenges for effective treatment options in veterinary ...
Sayara Bista   +12 more
doaj   +1 more source

Pyramidal Systems in Resistance Training

open access: yesEncyclopedia, 2021
Pyramidal systems refer to a particular type of resistance training in which sets are performed with increasing (or decreasing) weight, in such a way that the number of repetitions is low when the weight is high (and vice versa). Multiple implementations
Grégoire Hugues Cattan
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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