Results 31 to 40 of about 5,920,428 (283)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Within-individual design for assessing true individual responses in resistance training-induced muscle hypertrophy

Frontiers in Sports and Active Living
Understanding interindividual variability in muscle hypertrophy in response to resistance training (RT) is a key focus of contemporary research. Common aims include identifying determinants of variability and recognizing individuals who do not respond to
Talisson Santos Chaves, Deivid Gomes da Silva, Manoel Emílio Lixandrão, Cleiton Augusto Libardi   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Older adults, clinicians, and researchers’ preferences for measuring adherence to resistance and balance exercises

BMC Geriatrics, 2023
Background Resistance and balance training are important exercise interventions for older populations living with chronic diseases. Accurately measuring if an individual is adhering to exercises as prescribed is important to determine if lack of ...
Caitlin McArthur, Gabriella Duhaime, David Gonzalez, Nanna Notthoff, Olga Theou, Scott Kehler, Adria Quigley   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

In vitro activity of robenidine analogue NCL195 against methicillin-resistant Staphylococcus pseudintermedius

Microbiology Spectrum
The rise of difficult-to-treat infections among companion animals, particularly the increasing incidence of methicillin-resistant Staphylococcus pseudintermedius (MRSP) in dogs poses significant challenges for effective treatment options in veterinary ...
Sayara Bista, Hang Thi Nguyen, Tatiana P. Soares da Costa, Lucy Woolford, Mark A. T. Blaskovich, Tania Veltman, Kelly A. Young, Adam McCluskey, Meng Siak, Stephen W. Page, Henrietta Venter, Darren J. Trott, Abiodun D. Ogunniyi   +12 more
doaj   +1 more source

Residual Impact of Concurrent, Resistance, and High-Intensity Interval Training on Fasting Measures of Glucose Metabolism in Women With Insulin Resistance

Frontiers in Physiology, 2021
We sought to assess the residual effects (post 72-h training cessation) on fasting plasma glucose (FPG) and fasting insulin (FI) after 12-weeks of high-intensity interval training (HIIT), resistance training (RT), or concurrent training (CT) in women ...
Cristian Alvarez, Emmanuel Gomes Ciolac, Guilherme Veiga Guimarães, David C Andrade, Manuel Vasquez-Muñoz, Matías Monsalves-Álvarez, Matías Monsalves-Álvarez, Pedro Delgado-Floody, Alicia M. Alonso-Martínez, Mikel Izquierdo, Mikel Izquierdo   +10 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Grape by-products from the wine industry – an untapped sustainable resource for application in animal skin health preservation and treatment

Frontiers in Pharmacology
The all-wine industry is projected to generate over US$528 billion in sales globally by 2025, and like many mass-producing industries, it too generates significant waste and by-products, much of which ends up in landfill.
Wanting Chen, Wanting Chen, Preeti Pandey, Zyta M. Ziora, Zyta M. Ziora, Anjana Jayasree, Anjana Jayasree, Harendra S. Parekh, Harendra S. Parekh   +8 more
doaj   +1 more source