Results 71 to 80 of about 6,979 (181)

Specialized pro-resolution mediators in the bladder: effects of resolvin E1 on diabetic bladder dysfunction in the type 1 diabetic male Akita mouse model

BMC Urology
Background One of the most common, but least studied, diabetic complication is diabetic bladder dysfunction. Current therapies include glucose control and symptom-based interventions.
Anissa Cervantes, Francis M. Hughes, Huixia Jin, J. Todd Purves   +3 more
doaj   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

Resolvin inflammation with pain [PDF]

Expert Opinion on Investigational Drugs, 2010
Background: Inflammation and pain coexist in conditions such as arthritis, inflammatory bowel disease, and lower back pain. The drugs currently used to treat the combination of inflammation and pain all have disadvantages. Thus, new drugs and new approaches are needed to treat inflammation with pain.
openaire   +2 more sources

Can Inflammation-Resolution Provide Clues to Treat Patients According to Their Plaque Phenotype?

Frontiers in Pharmacology, 2019
Inflammation-resolution is an active process that is governed in part by specialized pro-resolving mediators (SPMs) such as lipoxins, resolvins, protectins, and maresins.
Gabrielle Fredman
doaj   +1 more source

Osteoarthritis: Epidemiology, Diagnosis, and Treatment

MedComm, Volume 7, Issue 7, July 2026.
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru, Dongliang Yuan, Shide Jiang, Xiaoxuan Zhao, Xu Liu, Yusheng Li, Shuguang Liu, Yuxiang Wu   +7 more
wiley   +1 more source

The Association between Resolvin D1 Levels and Gestational Diabetes Mellitus: Implications for Perinatal Outcomes

Gynecology Obstetrics & Reproductive Medicine
OBJECTIVE: To evaluate maternal Resolvin D1 levels in women with gestational diabetes mellitus (GDM) and investigate the association between perinatal outcomes.
Zeynep Seyhanli, Burak Bayraktar, Mevlut Bucak, Gulsan Karabay, Betul Tokgoz Cakir, Can Ozan Ulusoy, Gizem Aktemur, Selver Ozge Sefik, Serap Topkara Sucu, Sevki Celen, Ali Turhan Caglar   +10 more
doaj   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, Volume 13, Issue 33, 15 June 2026.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Microalgae Oil Attenuates Liver Fat Deposition in NAFLD via Modulation of Anti‐Lipogenic Genes and Insulin Signaling Pathways in HFD Mice

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Dietary microalgae oil might reverse hepatic lipid deposition in a mouse model of fatty liver. This intervention significantly improves the overall fatty liver condition by reducing lipid accumulation and simultaneously restoring insulin sensitivity. ABSTRACT Non‐alcoholic fatty liver disease (NAFLD) is a leading cause of liver‐related mortality and ...
Athba AlQahtani, Mingjie Wang, Liping Liu, Liyuan Ran, Chao Liu, Yun Liang, Jinhui Yu, Yingjie Wu, Qingbo Guan   +8 more
wiley   +1 more source

Eicosapentaenoic Acid Enhances the Effects of Mesenchymal Stromal Cell Therapy in Experimental Allergic Asthma

Frontiers in Immunology, 2018
Asthma is characterized by chronic lung inflammation and airway hyperresponsiveness. Despite recent advances in the understanding of its pathophysiology, asthma remains a major public health problem and, at present, there are no effective interventions ...
Soraia Carvalho Abreu, Soraia Carvalho Abreu, Miquéias Lopes-Pacheco, Miquéias Lopes-Pacheco, Adriana Lopes da Silva, Debora Gonçalves Xisto, Tainá Batista de Oliveira, Jamil Zola Kitoko, Jamil Zola Kitoko, Lígia Lins de Castro, Natália Recardo Amorim, Vanessa Martins, Luisa H. A. Silva, Cassiano Felippe Gonçalves-de-Albuquerque, Cassiano Felippe Gonçalves-de-Albuquerque, Hugo Caire de Castro Faria-Neto, Priscilla Christina Olsen, Daniel Jay Weiss, Marcelo Marcos Morales, Marcelo Marcos Morales, Bruno Lourenço Diaz, Patricia Rieken Macêdo Rocco, Patricia Rieken Macêdo Rocco   +22 more
doaj   +1 more source

Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats

Frontiers in Molecular Neuroscience, 2017
Antinociceptive pathways are activated in the periphery in inflammatory pain, for instance resolvins and opioid peptides. Resolvins are biosynthesized from omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid ...
Beatrice Oehler, Milad Mohammadi, Cristina Perpina Viciano, Dagmar Hackel, Carsten Hoffmann, Carsten Hoffmann, Alexander Brack, Heike L. Rittner   +7 more
doaj   +1 more source