Results 51 to 60 of about 6,979 (181)

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis, Leonardo Mancini, Panos Afouxenides, Andrea Roccuzzo, IADR IRG Peri‐implantitis Best Evidence Consensus Working Group 1, Tara Aghaloo, Georgios Belibasakis, Nagihan Bostanci, Li Dehua, Nikolaos Donos, Alpdogan Kantarci, Alireza Moshaverinia, Flavia Pirih, Mia Rakic, Frank Schwarz, Sukirth Ganesan   +15 more
wiley   +1 more source

The Lipid Mediator Resolvin D1 Reduces the Skin Inflammation and Oxidative Stress Induced by UV Irradiation in Hairless Mice

Frontiers in Pharmacology, 2018
UV irradiation-induced oxidative stress and inflammation contribute to the development of skin diseases. Therefore, targeting oxidative stress and inflammation might contribute to reduce skin diseases.
Priscila Saito, Cristina P. B. Melo, Renata M. Martinez, Renata M. Martinez, Victor Fattori, Talita L. C. Cezar, Ingrid C. Pinto, Allan J. C. Bussmann, Josiane A. Vignoli, Sandra R. Georgetti, Marcela M. Baracat, Waldiceu A. Verri, Rubia Casagrande   +12 more
doaj   +1 more source

Resolvins resolve to heal mucosal wounds [PDF]

Proceedings of the National Academy of Sciences, 2020
Surfaces lined by single or multiple layers of epithelial cells, termed mucosal surfaces, function as selectively permeable barriers that partition the host from the outside world. Given their proximity to microbes and microbial antigens, intestinal epithelial cells (IECs) have evolved mechanisms to maintain barrier function and to aid in promoting ...
openaire   +2 more sources

Resolvins and protectins: mediating solutions to inflammation [PDF]

British Journal of Pharmacology, 2009
Resolution of inflammation has historically been viewed as a passive process, occurring as a result of the withdrawal of pro‐inflammatory signals, including lipid mediators such as leukotrienes and prostaglandins. Thus, most anti‐inflammatory drugs have traditionally targeted primarily mediator pathways that are engaged at the onset of inflammation ...
Payal, Kohli, Bruce D, Levy
openaire   +2 more sources

Back to the Eosinophil: Resolvin Spatiotemporal Regulation

American Journal of Respiratory Cell and Molecular Biology, 2023
Eosinophils are granulocytes that home to sites of infection and injury, where they can initiate and drive host defense and allergic inflammatory responses. Eosinophil accumulation at different mucosal sites, including the lung and gastrointestinal tract, is also strongly linked with disease pathogenesis (1–3).
Donovan, Chantal, Barnes, Jessica L., Kim, Richard Y.   +2 more
openaire   +2 more sources

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Resolvin D2 Restrains Th1 Immunity and Prevents Alveolar Bone Loss in Murine Periodontitis

Frontiers in Immunology, 2018
Periodontitis is an infectious inflammatory disease of the supporting structures of the teeth. Resolvins are part of a large family of specialized pro-resolving lipid mediators that enhance active resolution of inflammation and return of inflammatory ...
Gabriel Mizraji, Gabriel Mizraji, Oded Heyman, Thomas E. Van Dyke, Asaf Wilensky   +4 more
doaj   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje, Ettore Amerio, Irene Mallor, Conrado Aparicio   +3 more
wiley   +1 more source

Pro-resolving lipid mediators (SPMs) and their actions in regulating miRNA in novel resolution circuits in inflammation

Frontiers in Immunology, 2012
Unresolved inflammation is associated with several widely occurring diseases such as arthritis, periodontal diseases, cancer, and atherosclerosis.
Charles N Serhan, Antonio eRecchiuti
doaj   +1 more source