Results 41 to 50 of about 6,979 (181)
Frontiers in Psychiatry, 2020 Inflammation has been identified as one of the main pathophysiological mechanisms underlying neuropsychiatric and neurodegenerative disorders. Despite the role of inflammation in those conditions, there is still a lack of effective anti-inflammatory ...
Juliette Giacobbe +4 more
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Lipoxins and Resolvins in Patients With Pancreatic Cancer: A Preliminary Report
Frontiers in Oncology, 2022 Eicosanoids are bioactive lipids derived from arachidonic acid, which have emerged as key regulators of a wide variety of pathophysiological processes in recent times and are implicated as mediators of gastrointestinal cancer.
Wojciech Blogowski +4 more
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The role of Resolvin D1 in liver diseases
Prostaglandins & Other Lipid Mediators, 2022 The liver is a parenchymatous organ closely related to immunity, detoxification and metabolism of the three major nutrients. The inflammatory response is a protective mechanism of the body to eliminate harmful stimuli. However, continuous inflammatory stimulation leads to occurrence of many liver diseases and brings great social burden.
Mei, Yang +3 more
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Indian Journal of Dental ResearchObjectives: This study aimed to evaluate the interaction of Resolvin E1 with macrophage-associated inflammatory markers and assess its potential role in macrophage polarization relevant to root resorption therapy. Methods: Molecular docking was performed
Nandini Suresh, Alan M. Punnoose
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Resolvin D1 and Resolvin D5 Lower Antibiotic Doses in Infection
The FASEB Journal, 2013 Underlying mechanisms for how bacterial infections contribute to active resolution of acute inflammation are unknown. Here, we carried out LM‐metabololipidomics following Escherichia coli (E. coli) infections in mice for temporal identification of pro‐inflammatory (prostaglandins and ...
Nan Chiang +3 more
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Formation of lipoxins and resolvins in human leukocytes
Prostaglandins & Other Lipid Mediators, 2023 Specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins are formed by the consecutive action of 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- or 15-lipoxygenases using arachidonic acid, eicosapentaenoic acid or docosahexaenoic acid as substrate.
Kahnt, Astrid Stefanie +2 more
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Advanced Healthcare Materials, EarlyView.Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha +9 more
wiley +1 more source
The potential role of n-3 fatty acids and their lipid mediators on asthmatic airway inflammation
Frontiers in ImmunologyAsthma, is a common, significant and diverse condition marked by persistent airway inflammation, with a major impact on human health worldwide. The predisposing factors for asthma are complex and widespread.
Yuan Tian +3 more
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Resolvin D2 attenuates chronic pain–induced depression‐like behavior in mice
Neuropsychopharmacology Reports, 2021 Aim We previously demonstrated that intracerebroventricular injection of resolvin D2 (RvD2), a bioactive lipid mediator derived from docosahexaenoic acid, ameliorated depression‐like behavior in lipopolysaccharide‐induced and chronic mild stress–induced ...
Hiroe Suzuki +3 more
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TRIM31–LOX‐1 Axis: A Novel Therapeutic Frontier in Atherosclerosis
iNew Medicine, EarlyView.ABSTRACT Atherosclerosis, driven by a vicious cycle of lipid accumulation and chronic inflammation, underlies most cardiovascular diseases. Macrophages exacerbate this process by internalizing oxidized low‐density lipoprotein (oxLDL), forming foam cells, and releasing inflammatory mediators. A recent study published in Circulation identified the TRIM31–
Qian Zhang, Cheng Xue Qin
wiley +1 more source