Results 21 to 30 of about 8,778 (174)
Journal of Lipid Research, 2023 A characteristic fragmentation was observed for PUFAs that contain allylic vicinal diol groups (resolvin D1, D2, D4, E3, lipoxin A4, B4, and maresin 2), which were derivatized with N,N-dimethylethylenediamine (DMED), in positive-ion ESI-MS/MS.
Huibin Zhu +5 more
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
The Role of Specialized Pro-Resolving Mediators in Cystic Fibrosis Airways Disease
Frontiers in Pharmacology, 2020 Cystic Fibrosis (CF) is a recessive genetic disease due to mutations of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene encoding the CFTR chloride channel. The ion transport abnormalities related to CFTR mutation generate a dehydrated
Maelle Briottet +2 more
doaj +1 more source
Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. [PDF]
PLoS ONE, 2014 The critical fatty acids Docosahexaenoic Acid (DHA) and Arachidonic Acid (AA) decline in preterm infants within the first postnatal week and are associated with neonatal morbidities, including bronchopulmonary dysplasia (BPD).
Camilia R Martin +7 more
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Neural Regeneration Research, 2023 Physical exercise effectively alleviates chronic pain associated with complex regional pain syndrome type-I. However, the mechanism of exercise-induced analgesia has not been clarified.
Xin Jia +5 more
doaj +1 more source
Role of Resolvins in Inflammatory and Neuropathic Pain
Pharmaceuticals, 2023 Chronic pain is an unpleasant experience associated with actual or potential tissue damage. Inflammatory pain alerts the body to inflammation and promotes healing; however, unresolved inflammation can lead to chronic pain.
Jaeik Park +5 more
doaj +1 more source
Modulation of the activities of neuronal ion channels by fatty acid-derived pro-resolvents
Frontiers in Physiology, 2016 Progress of inflammation depends on the balance between two biological mechanisms: pro-inflammatory and pro-resolving processes. Many extracellular and intracellular molecular components including cytokines, growth factors, steroids, neurotransmitters ...
Geunyeol Choi +2 more
doaj +1 more source
Pro-Resolving Ligands Orchestrate Phagocytosis
Frontiers in Immunology, 2021 The resolution of inflammation is a tissue protective program that is governed by several factors including specialized pro-resolving mediators (SPMs), proteins, gasses and nucleotides. Pro-resolving mediators activate counterregulatory programs to quell
Christa Decker +2 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 15 ...
Nils Helge Schebb +22 more
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First Total Synthesis Of 4(r),17(r)-resolvin D6 Stereoisomer, A Potent Neuroprotective Docosanoid
, 2022 The first total synthesis of a novel neuroprotective Resolvin D6 enantiomer, 4(R),17(R)-Resolvin D6, is described. Resolvin D6 is a lipid mediator derived from docosahexaenoic acid (DHA, C22:6, ω-3) with anti-inflammatory properties.
Nshimiyimana, Robert +5 more
core +1 more source