Results 21 to 30 of about 6,998 (140)

Serum Resolvin E1 Levels and Its Relationship with Disease Activity in Ulcerative Colitis

open access: yesGastroenterology Research and Practice, 2019
Background. Resolvins originate from ω-3 PUFA (polyunsaturated fatty acid) precursors and play a role in the resolution of inflammation. The aim of this study was to determine the serum Resolvin E1 levels in patients with ulcerative colitis (UC) and to ...
Süleyman Günay   +4 more
doaj   +1 more source

Role of Resolvins in Inflammatory and Neuropathic Pain

open access: yesPharmaceuticals, 2023
Chronic pain is an unpleasant experience associated with actual or potential tissue damage. Inflammatory pain alerts the body to inflammation and promotes healing; however, unresolved inflammation can lead to chronic pain.
Jaeik Park   +5 more
doaj   +1 more source

Modulation of the activities of neuronal ion channels by fatty acid-derived pro-resolvents

open access: yesFrontiers in Physiology, 2016
Progress of inflammation depends on the balance between two biological mechanisms: pro-inflammatory and pro-resolving processes. Many extracellular and intracellular molecular components including cytokines, growth factors, steroids, neurotransmitters ...
Geunyeol Choi   +2 more
doaj   +1 more source

Association of resolvin level in pregnant women with preeclampsia and metabolic syndrome

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2020
Objective: Preeclampsia (PE) and Metabolic syndrome (MetS) are multifactorial conditions and are major causes of maternal and neonatal morbidity and mortality worldwide. Both conditions are pro-inflammatory and can be causative factor for vascular damage.
Sabah Farhat   +5 more
doaj   +1 more source

Pro-Resolving Ligands Orchestrate Phagocytosis

open access: yesFrontiers in Immunology, 2021
The resolution of inflammation is a tissue protective program that is governed by several factors including specialized pro-resolving mediators (SPMs), proteins, gasses and nucleotides. Pro-resolving mediators activate counterregulatory programs to quell
Christa Decker   +2 more
doaj   +1 more source

Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?

open access: yesFrontiers in Pharmacology, 2022
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 15 ...
Nils Helge Schebb   +22 more
doaj   +1 more source

Host Lipid Mediators in Leprosy: The Hypothesized Contributions to Pathogenesis

open access: yesFrontiers in Immunology, 2018
The spectrum of clinical forms observed in leprosy and its pathogenesis are dictated by the host’s immune response against Mycobacterium leprae, the etiological agent of leprosy.
Carlos A. M. Silva, John T. Belisle
doaj   +1 more source

The Anti-Inflammatory Role of Omega-3 Polyunsaturated Fatty Acids Metabolites in Pre-Clinical Models of Psychiatric, Neurodegenerative, and Neurological Disorders

open access: yesFrontiers in Psychiatry, 2020
Inflammation has been identified as one of the main pathophysiological mechanisms underlying neuropsychiatric and neurodegenerative disorders. Despite the role of inflammation in those conditions, there is still a lack of effective anti-inflammatory ...
Juliette Giacobbe   +4 more
doaj   +1 more source

Lipoxins and Resolvins in Patients With Pancreatic Cancer: A Preliminary Report

open access: yesFrontiers in Oncology, 2022
Eicosanoids are bioactive lipids derived from arachidonic acid, which have emerged as key regulators of a wide variety of pathophysiological processes in recent times and are implicated as mediators of gastrointestinal cancer.
Wojciech Blogowski   +4 more
doaj   +1 more source

Role of Resolvin E1 in macrophage polarization as a therapeutic strategy for root resorption: In silico and in vitro analysis

open access: yesIndian Journal of Dental Research
Objectives: This study aimed to evaluate the interaction of Resolvin E1 with macrophage-associated inflammatory markers and assess its potential role in macrophage polarization relevant to root resorption therapy. Methods: Molecular docking was performed
Nandini Suresh, Alan M. Punnoose
doaj   +1 more source

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