Results 21 to 30 of about 6,979 (181)
Resolvins and Protectins in Inflammation Resolution [PDF]
Chemical Reviews, 2011 The critical role of inflammatory processes in health and disease has long been recognized,1 yet the detailed molecular mechanisms and biological events that regulate the progression and resolution of inflammation remain of interest. A number of recent investigations have provided strong evidence that the resolution of inflammation is not a passive ...
Charles N, Serhan, Nicos A, Petasis
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The Role of Specialized Pro-Resolving Mediators in Cystic Fibrosis Airways Disease
Frontiers in Pharmacology, 2020 Cystic Fibrosis (CF) is a recessive genetic disease due to mutations of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene encoding the CFTR chloride channel. The ion transport abnormalities related to CFTR mutation generate a dehydrated
Maelle Briottet +2 more
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Chemistry & Biology, 2013 In this issue of Chemistry & Biology, Dalli and colleagues report the chemical structures of resolvin D3 (RvD3) and aspirin-triggered RvD3, derived from the ω3-fatty acid docosahexaenoic acid. These compounds have a specific temporal appearance within inflammation resolution and display anti-inflammatory and proresolving properties.
Haeggström, Jesper Z., Hamberg, Mats
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Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. [PDF]
PLoS ONE, 2014 The critical fatty acids Docosahexaenoic Acid (DHA) and Arachidonic Acid (AA) decline in preterm infants within the first postnatal week and are associated with neonatal morbidities, including bronchopulmonary dysplasia (BPD).
Camilia R Martin +7 more
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Resolvin E1 and Cytokines Environment in Skeletally Immature and Adult ACL Tears
Frontiers in Medicine, 2021 The intra-articular synovial fluid environment in skeletally immature patients following an ACL tear is complex and remains undefined. Levels of inflammatory and anti-inflammatory cytokines change significantly in response to trauma and collectively ...
Marco Turati +30 more
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Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia [PDF]
The American Journal of Pathology, 2016 Acute lung injury is a life-threatening condition caused by disruption of the alveolar-capillary barrier leading to edema, influx of inflammatory leukocytes, and impaired gas exchange. Specialized proresolving mediators biosynthesized from essential fatty acids, such as docosahexaenoic acid, have tissue protective effects in acute inflammation. Herein,
Jennifer K, Colby +13 more
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Neural Regeneration Research, 2023 Physical exercise effectively alleviates chronic pain associated with complex regional pain syndrome type-I. However, the mechanism of exercise-induced analgesia has not been clarified.
Xin Jia +5 more
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Serum Resolvin E1 Levels and Its Relationship with Disease Activity in Ulcerative Colitis
Gastroenterology Research and Practice, 2019 Background. Resolvins originate from ω-3 PUFA (polyunsaturated fatty acid) precursors and play a role in the resolution of inflammation. The aim of this study was to determine the serum Resolvin E1 levels in patients with ulcerative colitis (UC) and to ...
Süleyman Günay +4 more
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Modulation of the activities of neuronal ion channels by fatty acid-derived pro-resolvents
Frontiers in Physiology, 2016 Progress of inflammation depends on the balance between two biological mechanisms: pro-inflammatory and pro-resolving processes. Many extracellular and intracellular molecular components including cytokines, growth factors, steroids, neurotransmitters ...
Geunyeol Choi +2 more
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Resolvins as Regulators of the Immune System [PDF]
The Scientific World JOURNAL, 2010 Inflammation is the first response of the immune system to infection or injury, but excessive or inappropriate inflammatory responses contribute to a range of acute and chronic human diseases. Clinical assessment of dietary supplementation of ω-3 polyunsaturated fatty acids (i.e., eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) indicate ...
Hiroyuki Seki +3 more
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