Results 11 to 20 of about 6,979 (181)
Differential effects of resolvin D1 and resolvin E1 on cementoblast function
Journal of Periodontology, 2023 AbstractBackgroundResolvins are endogenous mediators of the resolution of inflammation. They are derived from omega‐3 polyunsaturated fatty acid precursors. Resolvin D1 (RvD1) and Resolvin E1 (RvE1) are the best‐characterized members for actively promoting periodontal regeneration in experimental animal models.
Bozkurt, Serife Buket +2 more
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The Journal of Experimental Medicine, 2002 Aspirin (ASA) is unique among current therapies because it acetylates cyclooxygenase (COX)-2 enabling the biosynthesis of R-containing precursors of endogenous antiinflammatory mediators. Here, we report that lipidomic analysis of exudates obtained in the resolution phase from mice treated with ASA and docosahexaenoic acid (DHA) (C22:6) produce a novel
Charles N. Serhan +6 more
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Resolvin E1 Regulates Th17 Function and T Cell Activation
Frontiers in Immunology, 2021 Resolvin E1 (RvE1) is a specialized pro-resolving lipid mediator derived from eicosapentaenoic acid and plays a critical role in resolving inflammation and tissue homeostasis. Th17 cells are a distinct group of T helper (Th) cells with tissue-destructive
Fatma Oner +10 more
doaj +1 more source
Omega 3 Fatty Acid and Skin Diseases
Frontiers in Immunology, 2021 Humans are exposed to various external environmental factors. Food intake is one of the most influential factors impacting daily lifestyle. Among nutrients obtained from foods, omega-3 polyunsaturated fatty acids (PUFAs) have various beneficial effects ...
Yu Sawada +2 more
doaj +1 more source
Resolvins and inflammatory pain [PDF]
F1000 Medicine Reports, 2011 Resolvins are a group of molecules derived from omega-3 fatty acids. They are part of a biochemical program that allows inflamed tissues to return to homeostasis once the need for the inflammatory response is over. Resolvins act in very low dose ranges in vitro and in vivo.
Sommer, Claudia, Birklein, Frank
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Biomolecules, 2022 A precision medicine approach is widely acknowledged to yield more effective therapeutic strategies in the treatment of patients with chronic inflammatory conditions than the prescriptive paradigm currently utilized in the management and treatment of ...
Jesmond Dalli +2 more
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Mast cells contribute to the resolution of allergic inflammation by releasing resolvin D1
Pharmacological Research, 2023 Background: Mast cells are initiators and main effectors of allergic inflammation, together with eosinophils, with whom they can interact in a physical and soluble cross-talk with marked pro-inflammatory features, the Allergic Effector Unit.
Pier Giorgio Puzzovio +7 more
doaj +1 more source
Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity
JCI Insight, 2021 Sepsis is a critical illness characterized by dysregulated inflammatory responses lacking counter-regulation. Specialized proresolving mediators are agonists for antiinflammation and for promoting resolution, and they are protective in preclinical sepsis
Bakr Jundi +10 more
doaj +1 more source
Journal of Lipid Research, 2023 A characteristic fragmentation was observed for PUFAs that contain allylic vicinal diol groups (resolvin D1, D2, D4, E3, lipoxin A4, B4, and maresin 2), which were derivatized with N,N-dimethylethylenediamine (DMED), in positive-ion ESI-MS/MS.
Huibin Zhu +5 more
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