Results 11 to 20 of about 6,998 (140)
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Omega 3 Fatty Acid and Skin Diseases
Frontiers in Immunology, 2021 Humans are exposed to various external environmental factors. Food intake is one of the most influential factors impacting daily lifestyle. Among nutrients obtained from foods, omega-3 polyunsaturated fatty acids (PUFAs) have various beneficial effects ...
Yu Sawada +2 more
doaj +1 more source
Biomolecules, 2022 A precision medicine approach is widely acknowledged to yield more effective therapeutic strategies in the treatment of patients with chronic inflammatory conditions than the prescriptive paradigm currently utilized in the management and treatment of ...
Jesmond Dalli +2 more
doaj +1 more source
Mast cells contribute to the resolution of allergic inflammation by releasing resolvin D1
Pharmacological Research, 2023 Background: Mast cells are initiators and main effectors of allergic inflammation, together with eosinophils, with whom they can interact in a physical and soluble cross-talk with marked pro-inflammatory features, the Allergic Effector Unit.
Pier Giorgio Puzzovio +7 more
doaj +1 more source
Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity
JCI Insight, 2021 Sepsis is a critical illness characterized by dysregulated inflammatory responses lacking counter-regulation. Specialized proresolving mediators are agonists for antiinflammation and for promoting resolution, and they are protective in preclinical sepsis
Bakr Jundi +10 more
doaj +1 more source
Journal of Lipid Research, 2023 A characteristic fragmentation was observed for PUFAs that contain allylic vicinal diol groups (resolvin D1, D2, D4, E3, lipoxin A4, B4, and maresin 2), which were derivatized with N,N-dimethylethylenediamine (DMED), in positive-ion ESI-MS/MS.
Huibin Zhu +5 more
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
The Role of Specialized Pro-Resolving Mediators in Cystic Fibrosis Airways Disease
Frontiers in Pharmacology, 2020 Cystic Fibrosis (CF) is a recessive genetic disease due to mutations of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene encoding the CFTR chloride channel. The ion transport abnormalities related to CFTR mutation generate a dehydrated
Maelle Briottet +2 more
doaj +1 more source
Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. [PDF]
PLoS ONE, 2014 The critical fatty acids Docosahexaenoic Acid (DHA) and Arachidonic Acid (AA) decline in preterm infants within the first postnatal week and are associated with neonatal morbidities, including bronchopulmonary dysplasia (BPD).
Camilia R Martin +7 more
doaj +1 more source
Resolvin E1 and Cytokines Environment in Skeletally Immature and Adult ACL Tears
Frontiers in Medicine, 2021 The intra-articular synovial fluid environment in skeletally immature patients following an ACL tear is complex and remains undefined. Levels of inflammatory and anti-inflammatory cytokines change significantly in response to trauma and collectively ...
Marco Turati +30 more
doaj +1 more source