Results 71 to 80 of about 9,624 (189)

Quantifying Benthic Biolayer Contributions to Whole‐Stream Reactivity by Unifying Surface and Subsurface Observations: Field Evidence and Theory

open access: yesWater Resources Research
The benthic biolayer is a shallow zone of reactive streambed sediments, widely believed to contribute disproportionately to whole‐stream reactions such as aerobic respiration and contaminant transformation.
Kevin R. Roche   +8 more
doaj   +1 more source

Resorufin as an Electron Acceptor in Glucose Oxidase-Catalyzed Oxidation of Glucose.

open access: yesChemical and Pharmaceutical Bulletin, 2000
Resorufin (1) has been found to act as an electron acceptor in glucose oxidase (GOD)-catalyzed oxidation of glucose. When a 1: 1: 1 mixture of solutions of 1 (5.0 microM), glucose, and GOD (4.0 mg/ml) in phosphate buffer (pH 7.4, 0.1 M) was incubated at 36 degrees C under aerobic conditions and the reaction was followed by a measurement of changes in ...
MAEDA, Hatsuo   +6 more
openaire   +3 more sources

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4399-4415, August 2026.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci   +15 more
wiley   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

Evaluation of the Antimicrobial Activity of Essential Oils and Nanoemulsions of Chrysopogon zizanioides and Schinus terebinthifolius Cultivated in Brazil

open access: yesChemistrySelect, Volume 11, Issue 26, 10 July 2026.
ABSTRACT This study evaluated the antimicrobial activity of Chrysopogon zizanioides (vetiver) and Schinus terebinthifolius (aroeira) essential oils (EO) and their nanoemulsions, along with chemical characterization of the EO. The major compounds in C.
Bruno Alcântara do Prado   +10 more
wiley   +1 more source

Enhanced Cytochrome P450 IA1 Activity of Self-Assembled Rat Hepatocyte Spheroids

open access: yesCell Transplantation, 1999
Primary rat hepatocytes can self-assemble to form multicellular spheroids when plated onto Primaria petri dishes. Spheroids have been observed to exhibit enhanced liver-specific functions and differentiated ultrastructure compared to monolayer cultures ...
Florence J. Wu   +4 more
doaj   +1 more source

In‐Gel Generated Palladium Nanostructures as Bioorthogonal Uncaging Reactors

open access: yesAdvanced NanoBiomed Research
In the quest to alleviate the severe side effects of chemotherapy, a promising approach is through prodrugs, an inactivate form of the drug that is administered systemically but activated locally.
Aisling McGuigan   +4 more
doaj   +1 more source

Standard Operating Procedure to Optimize Resazurin-Based Viability Assays

open access: yesBiosensors
The resazurin assay, also known as the Alamar Blue assay, stands as a cornerstone technique in cell biology, microbiology, and drug development. It assesses the viability of cells through the conversion of resazurin into highly fluorescent resorufin. The
Jessica Petiti   +2 more
doaj   +1 more source

FACS‐Sortable Triple Emulsion Picoreactors for Screening Reactions in Biphasic Environments

open access: yesAdvanced Materials Interfaces
Biphasic environments can enable successful chemical reactions where any single solvent results in poor substrate solubility or poor catalyst reactivity.
Samuel Thompson   +4 more
doaj   +1 more source

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