Results 61 to 70 of about 2,244,366 (395)
Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves [PDF]
Journal of the Serbian Chemical Society, 2018 The ultrasound-assisted extraction of Juglans nigra L. leaves was optimized with respect to total phenolic content (TP) of the extracts by varying the concentration of aqueous ethanol solution (E) and different solvent-to-solid ratio (S).
Gavrilović Marijana +5 more
doaj +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
The possibilities of wheat roller milling optimization using the response surface methodology [PDF]
Journal on Processing and Energy in Agriculture, 2017 Roller mills are one of the most frequently used grinding machines especially for cereal milling. Magnitude and type of the forces acting on particle depend on the set of roll parameters.
Fišteš Aleksandar +3 more
doaj +1 more source
Optimization of Anthocyanin Extraction from Saffron Petals with Response Surface Methodology [PDF]
, 2016 Optimum extraction conditions of anthocyanins from petals of saffron (Crocus sativus) using acidified ethanol as the solvent were revealed. The investigated factors were solvent to sample ratio (20:1–80:1), ethanol concentration (%), extraction ...
Ghorbani, M. +4 more
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Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Response surface methodology and its application in simulation [PDF]
Proceedings of the 25th conference on Winter simulation - WSC '93, 1993 The contents of this paper reflect a portion of the conference tutorial on the application of response surface methodology to simulation. In this paper we will present an outline of the methodology and give a simple example of its application to a two variable optimization problem.
Peter D. Welch, Sarah J. Hood
openaire +1 more source
On some aspects of second order response surface methodology : a thesis presented in partial fulfilment of the requirements for the degree of M. Sc. in Mathematics at Massey University [PDF]
, 1972 A unified development of the theoretical basis of response surface methodology, particularly as it applies to second order response surfaces, is presented.
Thomas, Vernon John
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A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source