Results 81 to 90 of about 7,824 (204)

Development and validation of portable, field-deployable Ebola virus point-of-encounter diagnostic assay for wildlife surveillance

One Health Outlook, 2021
Early detection of Ebola virus spillover into wildlife is crucial for rapid response. We developed and validated a portable, cold-chain independent Ebola virus RT-qPCR assay.
Dania M. Figueroa, Eeva Kuisma, M. Jeremiah Matson, Alain U. Ondzie, Trent Bushmaker, Stephanie N. Seifert, Francine Ntoumi, Beatriz Escudero-Pérez, César Muñoz-Fontela, Chris Walzer, Sarah H. Olson, Cynthia Goma-Nkoua, Jean-Vivien Mombouli, Robert J. Fischer, Vincent J. Munster   +14 more
doaj   +1 more source

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi, Asiyeh Jebelli, Parisa Shiri Aghbash, Behzad Baradaran, Mohammad Amini, Fatemeh Oroojalian, Nasser Pouladi, Hossein Bannazadeh Baghi, Miguel de la Guardia, Amir Ali Mokhtarzadeh   +9 more
wiley   +1 more source

Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015

Emerging Infectious Diseases, 2018
In August 2015, a nonhuman primate facility south of Manila, the Philippines, noted unusual deaths of 6 cynomolgus monkeys (Macaca fascicularis), characterized by generalized rashes, inappetence, or sudden death.
Catalino Demetria, Ina Smith, Titus Tan, Daniel Villarico, Edson Michael Simon, Rex Centeno, Mary Tachedjian, Satoshi Taniguchi, Masayuki Shimojima, Noel Lee J. Miranda, Mary Elizabeth Miranda, Melissa Marie R. Rondina, Rowena Capistrano, Amado Tandoc, Glenn Marsh, Debbie Eagles, Ramses Cruz, Shuetsu Fukushi   +17 more
doaj   +1 more source

Ebolavirus evolution and emergence are associated with land use change

Ecological Monographs, Volume 95, Issue 1, February 2025.
Abstract Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution. Here, we show a positive association between land use change and the evolution and dispersal of Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV).
Christian E. Lange, Thomas R. Barnum, David J. McIver, Matthew LeBreton, Karen Saylors, Charles Kumakamba, Sara Lowes, Eduardo Montero, Robert L. Cohen   +8 more
wiley   +1 more source

Development of an Immunofluorescence Method for the Detection of Antibodies to Ebola Virus Subtype Reston by the Use of Recombinant Nucleoprotein‐Expressing HeLa Cells [PDF]

Microbiology and Immunology, 2002
AbstractAn indirect immunofluorescent assay (IFA) to detect Ebola virus subtype Reston (EBO‐R) antibodies was developed by the use of a HeLa cell line stably expressing EBO‐R nucleoprotein (NP). This IFA has a high specificity for the detection of EBO‐R IgG antibodies in both hyperimmune rabbit sera and monkey sera collected during an EBO‐R outbreak in
Tetsuro, Ikegami, Masayuki, Saijo, Masahiro, Niikura, Mary E G, Miranda, Alan B, Calaor, Marvin, Hernandez, Daria L, Manalo, Ichiro, Kurane, Yasuhiro, Yoshikawa, Shigeru, Morikawa   +9 more
openaire   +2 more sources

Inter‐Reader Agreement for Contrast‐Enhanced Ultrasound Liver Imaging Reporting and Data System Major Features and Final Categorization

Journal of Ultrasound in Medicine, Volume 44, Issue 2, Page 349-357, February 2025.
Objectives Contrast‐enhanced ultrasound (CEUS) Liver Imaging Reporting and Data System (LI‐RADS) is used to definitively diagnose hepatocellular carcinoma (HCC) in patients at risk. However, the user variability associated with CEUS LI‐RADS has not been validated in North American and European patients.
Cristina M. Kuon Yeng Escalante, Tania Siu Xiao, Yuko Kono, Fabio Piscaglia, Stephanie R. Wilson, Alexandra Medellin, Shuchi K. Rodgers, Virginia Planz, Aya Kamaya, David T. Fetzer, Annalisa Berzigotti, Paul S. Sidhu, Corinne E. Wessner, Kristen Bradigan, John R. Eisenbrey, Flemming Forsberg, Andrej Lyshchik, CEUS LI‐RADS Trial Group, Gibran T. Yusuf, Abid Suddle, Vasileios D. Rafailidis, Lorenzo Mulazzani, Alessandro Granito, Eleonora Terzi, Antonella Forgione, Alice Giamperoli, Bernardo Stefanini, Iuliana‐Pompilia Radu, Amit G. Singal   +28 more
wiley   +1 more source

Ecologic and Geographic Distribution of Filovirus Disease

Emerging Infectious Diseases, 2004
We used ecologic niche modeling of outbreaks and sporadic cases of filovirus-associated hemorrhagic fever (HF) to provide a large-scale perspective on the geographic and ecologic distributions of Ebola and Marburg viruses.
A. Townsend Peterson, John T. Bauer, James N. Mills   +2 more
doaj   +1 more source

Ebola virus disease 2014 [PDF]

, 2014
Ebola virus disease was irst described in 1976 originating from the Ebola River in the Democratic Republic of Congo. Since then, Ebola virus has become an important public health threat in Africa, and now it is of great concern worldwide due to the ...
Arellanos Soto, Daniel, Bravo de la Cruz, Verónica, Galán Huerta, Kame Alberto, Ramos Jiménez, Javier, Rivas Estilla, Ana María   +4 more
core  

Genetically humanized phenylketonuria mouse model as a testing tool for human genome editing in fertilized eggs

Journal of Inherited Metabolic Disease, Volume 48, Issue 1, January 2025.
Abstract Targeted genome editing has made significant advancements; however, safety and ethical issues have not been fully elucidated, resulting in strict control of the technique. We tested genome editing tools on gametes from a genetically humanized mouse model using a phenylketonuria (PKU) mouse model to gain insights into genome editing in human ...
Atsumi Tsuji‐Hosokawa, Iku Tsuchiya, Kie Shimizu, Miho Terao, Mito Yasuhara, Natsuho Miyamoto, Saki Kikuchi, Yuya Ogawa, Kazuaki Nakamura, Yoichi Matsubara, Shuji Takada   +10 more
wiley   +1 more source

Ebolavirus and Haemorrhagic Syndrome

Sultan Qaboos University Medical Journal, 2015
The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world’s most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in
Gerald A. Matua, Dirk M. Van der Wal, Rozzano C. Locsin   +2 more
doaj   +2 more sources