Results 31 to 40 of about 501,662 (286)
The frequency of mutations in advanced thyroid cancer in Japan: a single-center study
We analyzed the outcomes of genetic testing to study the frequency of mutations in advanced thyroid cancer in Japan. Patients (n = 96) with unresectable or metastatic thyroid carcinoma were included for retrospective chart review.
Soji Toda +8 more
doaj +1 more source
Activation of the Erk8 Mitogen-activated Protein (MAP) Kinase by RET/PTC3, a Constitutively Active Form of the RET Proto-oncogene [PDF]
Mitogen-activated protein (MAP) kinases have a central role in several biological functions, including cell adhesion and spreading, chemotaxis, cell cycle progression, differentiation, and apoptosis.
Acunzo, Mario +7 more
core +2 more sources
Henrik Skov Nielsen: At give ret, ret at ...
openaire +4 more sources
Next-generation sequencing (NGS) is of great benefit to clinical practice in terms of identifying genetic alterations. This study aims to clarify the gene background and its influence on thyroid tumors in the Chinese population.
Xu-Feng Chen +6 more
doaj +1 more source
THE SIGNIFICANCE OF NATO'S STRATEGIC CGNCEPT FOR DEFENCE AND SECURITY, ADOPTED IN LISBON IN NOVEMBER 2010 [PDF]
The Heads of State and Government of the NATO nations decided to fulfill the Alliance's mission in ensuring "their common defense and security”. When NATO has put into practice this Strategic Concept, the Alliance will be more "effective in a changing ...
Eugen BĂDĂLAN, Eugen SITEANU
doaj
2012 European Thyroid Association Guidelines for Metastatic Medullary Thyroid Cancer
Distant metastases are the main cause of death in patients with medullary thyroid cancer (MTC). These 21 recommendations focus on MTC patients with distant metastases and a detailed followup protocol of patients with biochemical or imaging evidence of ...
V V Voskoboynikov +2 more
doaj +1 more source
Germline genetic variants in pheochromocytoma/paraganglioma: single-center experience
Pheochromocytoma and paragangliomas (PPGLs) are rare neuroendocrine tumors carrying 25–40% pathogenic germline gene variants (PGVs). We evaluated clinical, laboratory, and germline molecular profile of 115 patients with pathologic (14 patients were ...
José V Lima Jr +6 more
doaj +1 more source
The Bytown Gunners: The History of Ottawa’s Artillery, 1855-2015 (Book Review) by Kenneth W. Reynolds [PDF]
Review of The Bytown Gunners: The History of Ottawa’s Artillery, 1855-2015 by Kenneth W ...
McNorgan, Major (Ret\u27d) M.R.
core +1 more source
RET mutation and increased angiogenesis in medullary thyroid carcinomas [PDF]
Advanced medullary thyroid cancers (MTCs) are now being treated with drugs that inhibit receptor tyrosine kinases, many of which involved in angiogenesis.
Acquaviva, Giorgia +16 more
core +1 more source
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source

