Results 71 to 80 of about 60,412 (260)

Ret-Dependent and Ret-Independent Mechanisms of Gfl-Induced Sensitization

Molecular Pain, 2011
Background: The GDNF family ligands (GFLs) are regulators of neurogenic inflammation and pain. We have previously shown that GFLs increase the release of the sensory neuron neuropeptide, calcitonin gene-related peptide (CGRP) from isolated mouse DRG. Results: Inhibitors of the mitogen-activated protein kinase (MAPK) pathway abolished the enhancement of
Meadows Rena M, Pittman Sherry K, Roy Shannon, Schmutzler Brian S, Hingtgen Cynthia M   +4 more
openaire   +3 more sources

When Nature Counts: Corporate Biodiversity Attention and Access to Bank Finance

Business Strategy and the Environment, EarlyView.
ABSTRACT This paper investigates whether corporate attention to biodiversity influences firms' access to bank loans, an overlooked question in the emerging biodiversity–finance literature. Using a novel, text‐based measure constructed from 446 biodiversity‐related keywords and applied to Chinese A‐share listed firms from 2000 to 2023, we show that ...
Ruxiao Li, Bo Zhang, Zhang‐Hangjian Chen, Hafiz Hoque   +3 more
wiley   +1 more source

Pathways to Carbon Neutrality: The Role of Environmental Governance, Environmental Technology, Renewable Energy Transition, and Economic Policy Uncertainty in Africa

Business Strategy and the Environment, EarlyView.
ABSTRACT As climate change and environmental deterioration continue to escalate due to substantial CO2 emissions, nations worldwide are implementing approaches to alleviate CO2 emissions and accomplish carbon neutrality (CNE) goals. The current study examined CNE objectives for five selected nations in Africa, spanning from 1990 to 2022.
John Wiredu, Emmanuel Nketiah, Simplice A. Asongu, Kingsley Takyi Agyei, Zijie Fan   +4 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Among Patients with RET Fusion–Positive Non‐Small Cell Lung Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom, Aaron C. Tan, Erminia Massarelli, Vivek Subbiah, Valentina Boni, Bruce Robinson, Lori J. Wirth, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Caroline E. McCoach   +11 more
wiley   +1 more source

Structure‐Function Tailoring of Plasmonic Nanomaterials for Thin‐Film Photovoltaics

Carbon Energy, EarlyView.
This review discusses the mechanisms and recent advancements of plasmonics in achieving effective light management to enhance the performance of thin‐film solar cells. It highlights applications in high‐performance perovskite solar cells and future‐oriented tandem solar cells.
Sen Jiang, Wenhan Yang, Annan Zhu, Yuexin Lin, Zhaohui Xie, Ran Chen, Wenjing Zhu, Jin Liu, Yingjie Zhu, Wenye Jiang, Zhiyuan Gu, Kaiyang Wang, Shengchun Yang, Nan Zhang, Chao Liang   +14 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth, Bruce Robinson, Valentina Boni, Daniel S.W. Tan, Caroline McCoach, Erminia Massarelli, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Vivek Subbiah   +10 more
wiley   +1 more source

Electrical resistance tomography for process intensification of gas–liquid stirred tanks: A comparison of linear back projection and sensitivity conjugate gradient algorithms

The Canadian Journal of Chemical Engineering, EarlyView.
Monitoring gas–liquid dynamics using Electrical resistance tomography for process intensification in stirred tanks Abstract Electrical resistance tomography (ERT) is a non‐invasive technique widely applied to the study of multiphase flows, where phases exhibit different electrical properties.
Federico Alberini, Giuseppina Montante, Alessandro Paglianti   +2 more
wiley   +1 more source

Review of CFD modelling techniques for single‐phase and multiphase flow in static mixers

The Canadian Journal of Chemical Engineering, EarlyView.
This review synthesizes computational fluid dynamics (CFD) approaches for static mixers, linking hydrodynamics to pressure drop, particle/droplet distributions, mixing metrics, and heat‐transfer performance to guide modelling choices and design decisions. Abstract Static mixers enable compact and low‐energy intensification.
Jussan Jaeger, Sálvio Lima de Carvalho Neto, Silvio Edegar Weschenfelder, Glaucia Rodrigues Vieira de Almeida da Fonseca, Maria de Fátima Rodrigues da Cunha, Selene Maria Arruda Guelli Ulson de Souza, Evandro Balestrin, Adriano da Silva   +7 more
wiley   +1 more source

Overview of management and therapeutic advances in medullary thyroid cancer

Endocrine Oncology
Medullary thyroid carcinoma (MTC) is a rare cancer of the thyroid’s calcitonin-producing C cells. This review covers recent advances in MTC treatment, emphasizing surgical and systemic therapies.
Mark A Jara, Luciana Audi Castroneves
doaj   +1 more source

Multifocality and bilaterality in medullary thyroid cancer: basis for a proof-of-concept safety of lobectomy

European Thyroid Journal
Objective: At present, total thyroidectomy and central neck dissection are the surgical approaches recommended for the initial treatment of medullary thyroid cancer (MTC) independently of the size, number of tumor foci, age of patients, and other ...
Cappagli Virginia, Matrone Antonio, Bottici Valeria, Prete Alessandro, Ramone Teresa, Romei Cristina, Ciampi Raffaele, Ugolini Clara, Torregrossa Liborio, Piaggi Paolo, Elisei Rossella   +10 more
doaj   +1 more source