Results 121 to 130 of about 119,076 (326)

Biophysical Variation within the M1 Type of Ganglion Cell Photoreceptor

Cell Reports, 2017
Summary: Intrinsically photosensitive retinal ganglion cells of the M1 type encode environmental irradiance for functions that include circadian and pupillary regulation.
Alan J. Emanuel, Kush Kapur, Michael Tri H. Do   +2 more
doaj   +1 more source

Viral Vector-based Improvement of Optic Nerve Regeneration: Characterization of Individual Axons\u27 Growth Patterns and Synaptogenesis in a Visual Target [PDF]

, 2015
Lack of axon growth ability in the central nervous system poses a major barrier to achieving functional connectivity after injury. Thus, a non-transgenic regenerative approach to reinnervating targets has important implications in clinical and research ...
Blackmore, Murray G., Luo, Xueting, Salgueiro, Yadira, Yungher, Benjamin J.   +3 more
core   +1 more source

Anterior chamber flare and central macular thickness after trabeculectomy versus after phacoemulsification

Acta Ophthalmologica, EarlyView.
Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed, Jesper Høiberg Erichsen, Afrouz Ahmadzadeh, Lars Morten Holm, Line Kessel, Daniella Bach‐Holm   +5 more
wiley   +1 more source

Primary open‐angle glaucoma as a marker of upcoming Alzheimer's disease: A 20‐year Danish National Registry‐Based Study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate whether primary open‐angle glaucoma (POAG) is associated with an increased long‐term risk of developing Alzheimer's disease, given its shared neurodegenerative features. Methods A 20‐year longitudinal, registry‐based matched cohort study was conducted using Danish national health registries from 1998 to 2018. Individuals
Cecilia Kronvold, Signe Sperling, Sören Möller, Jakob Grauslund, Lonny Stokholm   +4 more
wiley   +1 more source

Editorial: Molecular dynamics of cognitive-motor impairment in neurodegenerative diseases

Frontiers in Molecular Neuroscience, 2023
Dhiraj Kumar, Dhiraj Kumar, Saba Noor, Manzar Alam, Manzar Alam, Md Imtaiyaz Hassan   +5 more
doaj   +1 more source

A model of ganglion axon pathways accounts for percepts elicited by retinal implants. [PDF]

, 2018
Degenerative retinal diseases such as retinitis pigmentosa and macular degeneration cause irreversible vision loss in more than 10 million people worldwide.
Beyeler, Michael, Boynton, Geoffrey M, Fine, Ione, Nanduri, Devyani, Rokem, Ariel, Weiland, James D   +5 more
core  

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Prognostic factors of optical coherence tomography angiography in intermediate and advanced primary open‐angle glaucoma: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract Conventional optical coherence tomography (OCT) has a floor effect in patients with severe visual field loss, such as seen in advanced primary open‐angle glaucoma (POAG). OCT angiography (OCTA) does not suffer from such a floor effect. However, which OCTA parameters are most useful for monitoring longitudinal progression is unclear.
Kamya Katarya, Victor A. de Vries, João Barbosa‐Breda, Luisa Sanchez Brea, Danilo Andrade De Jesus, Wishal D. Ramdas   +5 more
wiley   +1 more source

Prophylactic nicotinamide treatment protects from rotenone-induced neurodegeneration by increasing mitochondrial content and volume

Acta Neuropathologica Communications
Leber’s hereditary optic neuropathy (LHON) is driven by mtDNA mutations affecting Complex I presenting as progressive retinal ganglion cell dysfunction usually in the absence of extra-ophthalmic symptoms. There are no long-term neuroprotective agents for
Amin Otmani, Gauti Jóhannesson, Rune Brautaset, James R. Tribble, Pete A. Williams   +4 more
doaj   +1 more source

Effects of Hypoxic Preconditioning and Vascular Endothelial Growth Factor on the Survival of Isolated Primary Retinal Ganglion Cells [PDF]

, 2021
Hyoung Won Bae, Wungrak Choi, Ah Reum Hwang, Sang Yeop Lee, Gong Je Seong, Chan Yun Kim   +5 more
openalex   +1 more source