Results 11 to 20 of about 286,988 (401)
Inhibition of BDNF-AS Provides Neuroprotection for Retinal Ganglion Cells against Ischemic Injury. [PDF]
PLoS ONE, 2016 Brain-derived neurotrophic factor (BDNF) protects retinal ganglion cells against ischemia in ocular degenerative diseases. We aimed to determine the effect of BDNF-AS on the ischemic injury of retinal ganglion cells.The levels of BDNF and BDNF-AS were ...
Lifang Xu +4 more
doaj +2 more sources
Retinal Processing: Insights from Mathematical Modelling [PDF]
Journal of Imaging, 2022 The retina is the entrance of the visual system. Although based on common biophysical principles, the dynamics of retinal neurons are quite different from their cortical counterparts, raising interesting problems for modellers.
Bruno Cessac
doaj +2 more sources
Melanopsin ganglion cells are the most resistant retinal ganglion cell type to axonal injury in the rat retina. [PDF]
PLoS ONE, 2014 We report that the most common retinal ganglion cell type that remains after optic nerve transection is the M1 melanopsin ganglion cell. M1 ganglion cells are members of the intrinsically photosensitive retinal ganglion cell population that mediates non ...
Luis Pérez de Sevilla Müller +3 more
doaj +2 more sources
Activation of BMP-Smad1/5/8 signaling promotes survival of retinal ganglion cells after damage in vivo. [PDF]
PLoS ONE, 2012 While the essential role of bone morphogenetic protein (BMP) signaling in nervous system development is well established, its function in the adult CNS is poorly understood.
Yumi Ueki, Thomas A Reh
doaj +2 more sources
Neural Regeneration Research, 2023 [INLINE:1] Vision depends on accurate signal conduction from the retina to the brain through the optic nerve, an important part of the central nervous system that consists of bundles of axons originating from retinal ganglion cells.
Zhe Liu +12 more
doaj +1 more source
Feature Detection by Retinal Ganglion Cells.
Annual Review of Vision Science, 2022 Retinal circuits transform the pixel representation of photoreceptors into the feature representations of ganglion cells, whose axons transmit these representations to the brain.
D. Kerschensteiner
semanticscholar +1 more source
PTEN Expression Regulates Gap Junction Connectivity in the Retina
Frontiers in Neuroanatomy, 2021 Manipulation of the phosphatase and tensin homolog (PTEN) pathway has been suggested as a therapeutic approach to treat or prevent vision loss due to retinal disease.
Ashley M. Chen +7 more
doaj +1 more source
Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma. [PDF]
PLoS ONE, 2013 Glaucoma is a complex disease affecting an estimated 70 million people worldwide, characterised by the progressive degeneration of retinal ganglion cells and accompanying visual field loss.
Pete A Williams +6 more
doaj +1 more source
Intrinsically Photosensitive Retinal Ganglion Cells of the Human Retina
Frontiers in Neurology, 2021 Light profoundly affects our mental and physical health. In particular, light, when not delivered at the appropriate time, may have detrimental effects.
L. S. Mure
semanticscholar +1 more source
Neural Regeneration Research, 2023 Ras homolog enriched in brain (Rheb) is a small GTPase that activates mammalian target of rapamycin complex 1 (mTORC1). Previous studies have shown that constitutively active Rheb can enhance the regeneration of sensory axons after spinal cord injury by ...
Jikuan Jiang +7 more
doaj +1 more source