Results 231 to 240 of about 286,988 (401)

Direct reprogramming of fibroblasts into spiral ganglion neurons by defined transcription factors

open access: yesCell Proliferation, Volume 58, Issue 4, April 2025.
A combination of Ascl1, Pou4f1 and Myt1l was identified to promote functional reprogramming of cochlear spiral ganglion neurons based on biochemical, electrophysiological and single‐cell transcriptomic analyses. Abstract Degeneration of the cochlear spiral ganglion neurons (SGNs) is one of the major causes of sensorineural hearing loss and ...
Yuhang Huang   +11 more
wiley   +1 more source

How retinal microcircuits scale for ganglion cells of different size [PDF]

open access: hybrid, 1995
CK Kier   +2 more
openalex   +1 more source

Spatial distribution and functional integration of displaced retinal ganglion cells. [PDF]

open access: yesSci Rep
Duda S   +6 more
europepmc   +1 more source

Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells

open access: yesCell Proliferation, EarlyView.
hESCsdel18q exhibit delayed and impaired anterior neuroectoderm induction, leading to deficient RPE specification. hESCsdel18q lines showed dysregulation of TGFβ signalling, and endogenous overactivation of activin/nodal/TGFβ in hESCsdel18q leads to improper anterior/posterior neuroectodermal fate commitments.
Yingnan Lei   +9 more
wiley   +1 more source

Task-specific regional circuit adaptations in distinct mouse retinal ganglion cells. [PDF]

open access: yesSci Adv
Oesterle J   +6 more
europepmc   +1 more source

Tetrahedral Framework Nucleic Acid‐Based Delivery of DJ‐1‐saRNA Prevent Retinal Ischaemia–Reperfusion Injury via Inhibiting Ferroptosis

open access: yesCell Proliferation, EarlyView.
Illustration of the preparation of tFNAs‐DJ‐1 saRNAs complex and its inhibitory effects on ferroptosis in R28 and retina. ABSTRACT Retinal ischaemia/reperfusion injury (RI/RI) is the primary pathophysiological mechanism underlying retinal ischaemic diseases, potentially resulting in significant and irreversible visual impairment.
Xianggui Zhang   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy