Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization.
Journal of Medicinal Chemistry, 2015 Eye diseases characterized by excessive angiogenesis such as wet age-related macular degeneration, proliferative diabetic retinopathy, and retinopathy of prematurity are major causes of blindness.
Halesha D. Basavarajappa +13 more
semanticscholar +1 more source
CellsFunctional cell death pathways are essential for normal ocular vascular development and tissue homeostasis. As our understanding of necrosis-based cell death pathways has expanded, the inclusion of regulated forms, including necroptosis, ferroptosis, and
Yong-Seok Song +10 more
doaj +1 more source
Sphingolipids as emerging mediators in retina degeneration [PDF]
, 2019 The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber +3 more
core +1 more source
PLoS ONE, 2015 Retinopathy of prematurity, formerly known as a retrolental fibroplasia, is a leading cause of infantile blindness worldwide. Retinopathy of prematurity is caused by the failure of central retinal vessels to reach the retinal periphery, creating a ...
Yu-Ching Wu +6 more
semanticscholar +1 more source
Generative Adversarial Networks Synthesize Realistic OCT Images of the Retina [PDF]
arXiv, 2019 We report, to our knowledge, the first end-to-end application of Generative Adversarial Networks (GANs) towards the synthesis of Optical Coherence Tomography (OCT) images of the retina. Generative models have gained recent attention for the increasingly realistic images they can synthesize, given a sampling of a data type.
arxiv
Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusion [PDF]
, 2008 Purpose: To evaluate the effect of intravitreal bevacizumab (Avastin) injections on visual acuity (VA) and foveal retinal thickness in patients with macular oedema secondary to branch retinal vein occlusion.Methods: A prospective, non-comparative ...
Alge, C. S. +9 more
core +1 more source
Foveal neovascularization in a patient with Type 2 diabetes mellitus
Oman Journal of Ophthalmology, 2017 Retinal neovascularization in Diabetes mellitus (DM) is commonly seen at the optic disc and mid-periphery. It is rare at the fovea as the fovea is an avascular zone and there are very few case reports of foveal neovascularization in Type 1 DM.
Anisha Seth +4 more
doaj +1 more source
Ultrastructure of neurovascular changes in human diabetic retinopathy [PDF]
, 2018 The previous concept regarding diabetic retinopathy assigned a primary role to hyperglycemia-induced microvascular alterations, while neuronal and glial abnormalities were considered to be secondary to either ischemia or exudation.
Artico, Marco +9 more
core +1 more source
A smartphone-based tool for rapid, portable, and automated wide-field retinal imaging [PDF]
, 2018 Purpose:High-quality, wide-field retinal imaging is a valuable method for screening preventable, vision-threatening diseases of the retina. Smartphone-based retinal cameras hold promise for increasing access to retinal imaging, but variable image quality
Margolis, Todd
core +4 more sources
Comparison of Intravitreal Bevacizumab Upload Followed by a Dexamethasone Implant versus Dexamethasone Implant Monotherapy for Retinal Vein Occlusion with Macular Edema [PDF]
, 2012 Purpose: To compare the efficacy and safety of three intravitreal bevacizumab upload injections followed by a dexamethasone implant versus dexamethasone implant monotherapy in eyes with macular edema due to retinal vein occlusion.
Haritoglou, Christos +7 more
core +1 more source