Results 101 to 110 of about 399,940 (338)
In this review, we introduced the preparation methods of LDHzymes and discussed their catalytic activity and mechanisms. Subsequently, the applications of LDHzymes in biomedical were discussed. Finally, potential future work on LDHzymes was proposed to better design these new types of nanozymes.
Jiawei Cui +7 more
wiley +1 more source
The Effect of Bariatric Surgery on Diabetic Retinopathy: Good, Bad, or Both? [PDF]
Bariatric surgery, initially intended as a weight-loss procedure, is superior to standard lifestyle intervention and pharmacological therapy for type 2 diabetes in obese individuals.
Docherty, NG, Gorman, DM, Le Roux, CW
core +3 more sources
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
Pathological retinal neovascularization is a cause of vision loss in diseases including retinopathy of prematurity (ROP), wet age-related macular degeneration (AMD), and diabetic retinopathy. The Unfolded Protein Response (UPR) is an intracellular signal
Allyssa Bradley +9 more
doaj +1 more source
MicroRNA signature and function in retinal neovascularization
Ischemic retinopathies are clinically well-defined chronic microvascular complications characterized by gradually progressive alterations in the retinal microvasculature and a compensatory aberrant neovascularization of the eye. The subsequent metabolic deficiencies result in structural and functional alterations in the retina which is highly ...
Saloni Agrawal, Brahim Chaqour
openaire +3 more sources
Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long +13 more
wiley +1 more source
Phenotypic variance in Calpain-5 retinal degeneration
Purpose: To characterize the phenotype of patients with mild calpain-5 Neovascular Inflammatory Vitreoretinopathy (ADNIV). Observations: The CAPN5 p.R243L mutation is typically associated with onset in the twenties and severe, progressive uveitis ...
Peter H. Tang +7 more
doaj +1 more source
Lack of netrin-4 modulates pathologic neovascularization in the eye [PDF]
Netrins are a family of matrix-binding proteins that function as guidance signals. Netrin-4 displays pathologic roles in tumorigenesis and neovascularization.
Brunken, William J. +12 more
core +1 more source
BackgroundRetinal neovascularization, which is the pathological growth of new blood vessels, is associated with retinopathy of prematurity, neovascular age-related macular degeneration, diabetic retinopathy and retinal vein occlusion.
Y. Lee +6 more
semanticscholar +1 more source
Dietary Compound Chrysin Inhibits Retinal Neovascularization with Abnormal Capillaries in db/db Mice
Diabetic retinopathy (DR) develops in a significant proportion of patients with chronic diabetes, characterized by retinal macular edema and abnormal retinal vessel outgrowth leading to vision loss.
Min-Kyung Kang +7 more
semanticscholar +1 more source

