Results 101 to 110 of about 38,468 (270)

Residual U-Net Architecture for Retinal Layers in OCT Images with Choroidal Neovascularization [PDF]

, 2023
Miriam Zipporah B, Francis Xavier Christopher D   +1 more
openalex   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Comparison of the Effects of the Pattern Scan and Conventional Single Spot Panretinal Photocoagulation in Patients with Proliferative Diabetic Retinopathy; A Randomized Clinical Trial

مجله دانشکده پزشکی اصفهان, 2016
Background: The retinal laser photocoagulation is the gold standard treatment of the proliferative diabetic retinopathy. Nowadays, we can perform panretinal photocoagulation with single spot or pattern scan laser methods.
Alireza Jamshidimadad, Alireza Dehghani, Farzan Kianersi, Khodayar Golabchi, Heshmatollah Ghanbari, Mohamadreza Akhlaghi   +5 more
doaj  

Evaluating the Efficacy of Polyphenol‐Enriched Plant Extracts and Pathway Modulators in the Bone Marrow to Suppress Breast Cancer Progression

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
The combined therapy decreased inflammatory and angiogenic signaling and altered bone marrow cell profiles linked to tumor dormancy, indicating a potential approach to limit disease progression and reduce relapse risk in breast cancer. ABSTRACT Disseminated tumor cells (DTCs) in the bone marrow can survive in a dormant state and later reawaken to drive
Hayarpi Javrushyan, Gayane Petrosyan, Marika Mróz, Barbara Kusznierewicz, Yem Alharithi, Mikayel Ginovyan, Alina Maloyan, Nikolay Avtandilyan   +7 more
wiley   +1 more source

Soluble Epoxide Hydrolase Inhibitors Improve Cornea Alkali Wound Healing

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Soluble epoxide hydrolase (sEH) inhibition enhances corneal wound healing following alkali injury. (A) Schematic representation of corneal injury induced by NaOH or ammonia showing elevated sEH expression in corneal keratocytes. This leads to rapid hydrolysis of epoxy fatty acids (EpFAs), reducing their bioavailability and contributing to enhanced ...
Xiaowen Lu, Christophe Morisseau, Khushi Jain, Zhong Chen, Amy J. Estes, Darryl Zeldin, Artiom Gruzdev, Aniqa Ahmed, Haley Cook, Bruce D. Hammock, Mitchell A. Watsky   +10 more
wiley   +1 more source

Overproduction of 42 Amino Acids Long Amyloid Beta Leads to Activation of Secretory Autophagy and Development of Drusen‐Like Structures Originating From Retinal Pigment Epithelium

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
The role of 42 amino acids long amyloid beta (Aβ) in the retinal pigment epithelium (RPE) was investigated using 5xFAD mice model overproducing Aβ. The RPE cells of 5xFAD mice showed increased oxidative stress, accumulation of autophagy‐destined proteins, increased expression of secretory autophagy markers, and increase in epithelial‐to‐mesenchymal ...
Johanna Ruuth, Toni Tamminen, Elisa Toropainen, Heikki Tanila, Juha M. T. Hyttinen, Tarja Malm, Kai Kaarniranta, Ali Koskela   +7 more
wiley   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

The effects of anti‐VEGF and kinin B₁ receptor blockade on retinal inflammation in laser‐induced choroidal neovascularization [PDF]

, 2019
Soumaya Hachana, Olivier Fontaine, Przemysław Sapieha, Mark R. Lesk, Réjean Couture, Elvire Vaucher   +5 more
openalex   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, Volume 13, Issue 5, 4 March 2026.
ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation rates ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

The Cell-Matrix Interface: a Possible Target for Treating Retinal Vascular Related Pathologies

Journal of Ophthalmic & Vision Research, 2012
Retinal vasculature related pathologies account for a large proportion of global blindness. Choroidal neovascularization accompanying age-related macular degeneration is the largest cause of blindness in people over the age of 65 years, proliferative ...
Gopalan Gnanaguru, William J Brunken
doaj