Results 131 to 140 of about 402,915 (338)

Glaucomatous vertical vessel density asymmetry of the temporal raphe detected with optical coherence tomography angiography. [PDF]

open access: yes, 2020
Changes in retinal vasculature and ocular circulation may play an important role in the glaucoma development and progression. We evaluated the vertical asymmetry across the temporal raphe of the deep retinal layer vessel density, using swept-source ...
Araie, Makoto   +6 more
core  

Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy [PDF]

open access: yes, 2016
Diabetic retinopathy (DR) affects approximately one-third of diabetic patients and, if left untreated, progresses to proliferative DR (PDR) with associated vitreous hemorrhage, retinal detachment, iris neovascularization, glaucoma and irreversible ...
Bassuk, Alexander G.   +12 more
core   +2 more sources

Fluid/function correlation using AI‐based quantification versus central subfield thickness in treatment‐naïve and pre‐treated patients with neovascular AMD in a real‐world setting

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between best‐corrected visual acuity (BCVA) and quantitative macular fluid volumes, compared to central subfield thickness (CST) in treatment‐naïve and previously treated patients with active neovascular age‐related macular degeneration (nAMD).
Anna Eidenberger   +15 more
wiley   +1 more source

A novel tissue inhibitor of metalloproteinases-3 mutation reveals a common molecular phenotype in sorsby's fundus dystrophy [PDF]

open access: yes, 2000
Sorsby’s fundus dystrophy (SFD) is a dominantly inherited degenerative disease of the retina that leads to loss of vision in middle age. It has been shown to be caused by mutations in the gene for tissue inhibitor of metalloproteinases-3 (TIMP-3 ...
Barker, M.D.   +6 more
core   +1 more source

NADPH Oxidase 4-Derived H2O2 Promotes Aberrant Retinal Neovascularization via Activation of VEGF Receptor 2 Pathway in Oxygen-Induced Retinopathy

open access: yesJournal of Diabetes Research, 2015
NADPH oxidase 4 (Nox4) is a major isoform of NADPH oxidase in retinal endothelial cells. Our previous study suggests that upregulation of Nox4 in retinal endothelial cells contributes to retinal vascular leakage in diabetes.
Jingming Li, J. Wang, Sarah X. Zhang
semanticscholar   +1 more source

Power and clinical utility of mesopic microperimetry analysis strategies in age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose This study evaluates whether mesopic microperimetry (MMP) provides a more robust measure of retinal function compared to visual acuity (VA) in age‐related macular degeneration (AMD) clinical trials, with a focus on optimal analysis strategies. Method Fellow‐eyes of unilateral neovascular AMD were prospectively studied.
Francesco Cinque   +9 more
wiley   +1 more source

Neovascular age‐related macular degeneration without drusen

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks   +9 more
wiley   +1 more source

Pregnancy as a risk factor for central serous chorioretinopathy: A systematic review and meta‐analysis

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Pregnancy induces significant changes in the body, including increased peripheral and choroidal blood perfusion and an increased systemic corticosteroid level. Here, we systematically reviewed the evidence on pregnancy as a risk factor for developing central serous chorioretinopathy (CSC) and conducted a meta‐analysis to obtain a ...
Nathalie Skovgaard Eriksen   +15 more
wiley   +1 more source

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