Results 61 to 70 of about 3,600,316 (189)

Retinoblastoma. Part 1. Clinical presentations and diagnostic tools [PDF]

open access: yesКлиническая офтальмология, 2020
Retinoblastoma. Part 1. Clinical presentations and diagnostic tools S.V. Ivanova1, S.A. Kuleva1, N.N. Sadovnikova2, M.I. Komissarov2, M.N. Chistyakova2, A.V. Khokhlova1, N.A. Shchegoleva3 1N.N.
S.V. Ivanova   +6 more
doaj  

Bioactive Polymeric Nanoparticles of Moringa oleifera Induced Phyto-Photothermal Sensitization for the Enhanced Therapy of Retinoblastoma

open access: yesPharmaceutics, 2023
Treatment of retinoblastoma is limited due to its delayed detection and inaccesbility of drugs to reach the retina crossing the blood-retinal barrier. With the advancements in nanotechnology, photothermal therapy (PTT) employing plasmonic nanomaterials ...
Sushma Venkata Mudigunda   +3 more
doaj   +1 more source

The Retinoblastoma Protein in Osteosarcomagenesis [PDF]

open access: yes, 2012
Osteosarcoma is one of the most common primary non-hematologic bone tumors present in both children and adults. The etiology of most cases of osteosarcoma is unknown although a genetic predisposition is suspected. Most osteosarcomas are diagnosed before the age of 20, where the pathology is likely distinct from osteosarcoma diagnosed over the age of 60,
Elizabeth Kong, Philip W.
openaire   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription

open access: yeseLife, 2016
Newly born cells either continue to proliferate or exit the cell division cycle. This decision involves delaying expression of Cyclin E that promotes DNA replication.
Manzar Hossain, Bruce Stillman
doaj   +1 more source

Genetic variants of EcPV2 E6 and E7 in equine genital and oronasal squamous cell carcinoma

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Since its discovery in 2008, equine papillomavirus type 2 (EcPV2) has been detected in up to 100% of equine genital and up to 40% of equine oronasal squamous cell carcinomas (SCCs). Preliminary sequence data point to the existence of EcPV2 E6 and E7 oncogene variants compared to the British reference sequence from 2008.
Maya Jenner, Sabine Brandt
wiley   +1 more source

RBL2 (retinoblastoma-like 2) [PDF]

open access: yes, 2004
Review on RBL2 (retinoblastoma-like 2), with data on DNA, on the protein encoded, and where the gene is ...
Russo, G, Claudio, PP, Giordano, A
core   +1 more source

Recruitment of Antigen Presenting Cells to Skin Draining Lymph Node From HPV16E7-Expressing Skin Requires E7-Rb Interaction

open access: yesFrontiers in Immunology, 2018
“High-risk” human papillomaviruses (HPV) infect keratinocytes of squamous epithelia. The HPV16E7 protein induces epithelial hyperplasia by binding Rb family proteins and disrupting cell cycle termination.
Paula Kuo   +5 more
doaj   +1 more source

Familial Cancers Associated With Cancers of the Breast, Prostate, Colorectum, and Lung in Sweden

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Available epidemiological evidence shows that many cancers share familial risks, and this is increasingly confirmed by data on shared pathogenic germline gene variants between cancers. We decided to harness the world's largest resource on familial cancer to assess discordant familial risks for female breast (BC), prostate (PC), colorectal (CRC)
Frantisek Zitricky   +5 more
wiley   +1 more source

Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity

open access: yesCancer Management and Research, 2018
Daniel J Asby,1 Clare L Killick-Cole,1 Lisa J Boulter,1 William GB Singleton,1,2 Claire A Asby,3 Marcella J Wyatt,1 Neil U Barua,1,2 Alison S Bienemann,1 Steven S Gill1,2 1Functional Neurosurgery Research Group, Translational Health Sciences, Bristol ...
Asby DJ   +8 more
doaj  

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