Evidence for a mitochondrial localization of the retinoblastoma protein [PDF]
BMC Cell Biology, 2009 Abstract Background The retinoblastoma protein (Rb) plays a central role in the regulation of cell cycle, differentiation and apoptosis. In cancer cells, ablation of Rb function or its pathway is a consequence of genetic inactivation, viral oncoprotein binding or deregulated hyperphosphorylation.
Feracatu, I. +8 more
openaire +5 more sources
Protein-Protein Interaction Network Study Reveals New Possible Endocrine Disrupting Chemicals (EDC) ‘ Impact on Retinoblastoma [PDF]
, 2020 : Background: Retinoblastoma (RB) is a retinal-derived embryonic tumor. The illness severity at the time of presentation affects survival and preserves eyesight.
Samadi, Sina +5 more
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Frontiers in ImmunologyPurposeRetinoblastoma is the most common intraocular cancer in infants and children, with a significant potential for metastasis. The mini-peptide ribosomal protein L41 (RPL41) has demonstrated extensive antitumor effects in vitro by promoting the ...
Ye Li +6 more
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PLoS ONE, 2023 The retinoblastoma protein (Rb) is encoded by the RB1 tumor suppressor gene. Inactivation of RB1 by inherited or somatic mutation occurs in retinoblastoma and various other types of tumors.
Mireia Palomar-Siles +3 more
doaj +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
A gender-specific retinoblastoma-related protein in Volvox carteri implies a role for the retinoblastoma protein family in sexual development [PDF]
, 2008 Kianianmomeni A, Nematollahi G, Hallmann A. A gender-specific retinoblastoma-related protein in Volvox carteri implies a role for the retinoblastoma protein family in sexual development. Plant Cell.
Kianianmomeni, Arash +2 more
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Investigation of protein-protein interactions involving retinoblastoma binding protein 6 using immunoprecipitation and nuclear magnetic resonance spectroscopy [PDF]
, 2019 >Magister Scientiae - MScRetinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been shown to play a role in mRNA processing, cell cycle arrest and apoptosis.
Chen, Po-An
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FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Short linear motif core and flanking regions modulate retinoblastoma protein binding affinity and specificity [PDF]
, 2018 Pocket proteins retinoblastoma (pRb), p107 and p130 are negative regulators of cellular proliferation and multifunctional proteins regulating development, differentiation and chromatin structure.
Chemes, Lucia Beatriz +3 more
core +1 more source
Aspects of Diagnosis and Treatment of Retinoblastoma in Mongolia
Central Asian Journal of Medical Sciences, 2018 Objectives: To describe the clinical characteristics and the treatment outcome of retinoblastoma in Mongolian children. Methods: Data of all children diagnosed with retinoblastoma at the National Center for Maternal and Child Health of Mongolia from 1987
Tsengelmaa Chuluunbat +4 more
doaj +1 more source