Results 31 to 40 of about 50,847 (238)
Retinoblastoma makes its mark on imprinting in plants [PDF]
, 2008 Genomic imprinting results in the preferential expression of alleles from either the maternal or paternal chromosomes. This epigenetic process occurs in embryonic and extra-embryonic (placental) tissues of mammals, but only in the extra-embryonic ...
Gutierrez-Marcos, José F. +5 more
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RBBP8 (retinoblastoma binding protein 8) [PDF]
, 2009 Review on RBBP8 (retinoblastoma binding protein 8), with data on DNA, on the protein encoded, and where the gene is ...
Chinnadurai, G +2 more
core +1 more source
ASSOCIATION OF RS2069502 CYCLIN-DEPENDENT KINASE 4 GENE WITH BREAST CANCER [PDF]
Euromediterranean Biomedical Journal, 2020 The goal of this project was to evaluate the association of candidate genetic variant rs2069502 of the CDK4 gene with breast cancer and the effect of variant genotypes on the serum concentration of CDK4 enzyme and consequently, on the occurrence of ...
Dalya Shakir Al-owaidi
doaj +1 more source
Anti-Cancer Drugs Effective in Retinoblastoma: Based on a Protein-Protein Interaction Network [PDF]
, 2020 Background: This paper investigates the effects of potential drugs on differentially expressed genes (DEGs) associated with substantial alterations in retinoblastoma malignancy.Material and Methods: The GSE125903 dataset consisting of ten samples was ...
Samadi, Sina +5 more
core +2 more sources
Cancer Cell International, 2003 Background One of the major cellular serine/threonine protein phosphatases is protein phosphatase type 1 (PP1). Studies employing many eukaryotic systems all point to a crucial role for PP1 activity in controlling cell cycle progression.
Klover Peter +5 more
doaj +1 more source
Dental Research Journal, 2015 Background: The role of retinoblastoma (Rb) protein in cell cycle regulation prompted us to take up this study with the aim of assessing its role in the progression of oral cancer and to correlate with various clinicopathological parameters, including ...
Sunila Thomas +2 more
doaj +1 more source
Frontiers in Endocrinology, 2022 The retinoblastoma (RB) protein family members (pRB, p107 and p130) are key regulators of cell cycle progression, but also play crucial roles in apoptosis, and stem cell self-renewal and differentiation. RB proteins exert their effects through binding to
Juho-Antti Mäkelä +3 more
doaj +1 more source
Current Assessment and Management of Retinoblastoma
Clinical Pediatric Hematology-Oncology, 2019 Retinoblastoma is the most common intraocular malignancy in childhood. Diagnosis is currently made by ophthalmologists under general anesthesia as it is the gold standard for intraocular assessment.
Hee Won Chueh
doaj +1 more source
PLoS ONE, 2011 Disruption of cell cycle regulation is one mechanism proposed for how nuclear envelope protein mutation can cause disease. Thus far only a few nuclear envelope proteins have been tested/found to affect cell cycle progression: to identify others, 39 novel
Nadia Korfali +6 more
doaj +1 more source
Protein Phosphatase Type 1-Dependent Dephosphorylation of the Retinoblastoma Tumor Suppressor Protein in Ultraviolet-Irradiated Human Skin and Keratinocytes [PDF]
, 2000 This study provides evidence for the involvement of a type 1 protein serine/threonine phosphatase in the ultraviolet radiation-induced dephosphorylation of retinoblastoma tumor suppressor protein in human skin and cultured keratinocytes.
Thomas, Robert C., Edwards, Malcolm J.
core +1 more source