Results 11 to 20 of about 3,600,316 (189)

Post-translational modifications on the retinoblastoma protein

Journal of Biomedical Science, 2022
The retinoblastoma protein (pRb) functions as a cell cycle regulator controlling G1 to S phase transition and plays critical roles in tumour suppression. It is frequently inactivated in various tumours.
Linbin Zhou, Danny Siu-Chun Ng, Jason C. Yam, Li Jia Chen, Clement C. Tham, Chi Pui Pang, Wai Kit Chu   +6 more
doaj   +3 more sources

Expression of multidrug resistance proteins in retinoblastoma [PDF]

International Journal of Ophthalmology, 2017
AIM: To elucidate the mechanism of multidrug resistance in retinoblastoma, and to acquire more insights into in vivo drug resistance. METHODS: Three anticancer drug resistant Y79 human RB cells were generated against vincristine, etoposide or ...
Swati Shukla, Arpna Srivastava, Sunil Kumar, Usha Singh, Sandeep Goswami, Bhavna Chawla, Mandeep Singh Bajaj, Seema Kashyap, Jasbir Kaur   +8 more
doaj   +3 more sources

Correlation of gene expression with magnetic resonance imaging features of retinoblastoma: a multi-center radiogenomics validation study [PDF]

, 2023
OBJECTIVES To validate associations between MRI features and gene expression profiles in retinoblastoma, thereby evaluating the repeatability of radiogenomics in retinoblastoma.
Moll, Annette C., Sirin, Selma, Robin W. Jansen, Sophia Göricke, de Jong, Marcus C, Maeder, Philippe, Brisse, Hervé J., Paolo Galluzzi, Castelijns, Jonas A, de Jong, Marcus C., Pim de Graaf, de Graaf, Pim, Cardoen, Liesbeth, Liesbeth Cardoen, Uner, Ogul E, Hervé J. Brisse, Khashayar Roohollahi, On behalf of the European Retinoblastoma Imaging Collaboration, Grossniklaus, Hans, de Jong, Yvonne, de Bloeme, Christiaan M., Hans Grossniklaus, Jansen, Robin W., Annette C. Moll, Galluzzi, Paolo, Hubbard, G Baker, Josephine Dorsman, Jansen, Robin W, Philippe Maeder, Brisse, Hervé J, Jonas A. Castelijns, Hubbard, G. Baker, Moll, Annette C, Ogul E. Uner, Marcus C. de Jong, Christiaan M. de Bloeme, Dorsman, Josephine, Roohollahi, Khashayar, Selma Sirin, Göricke, Sophia, Paul van der Valk, Castelijns, Jonas A., G. Baker Hubbard, van der Valk, Paul, Yvonne de Jong, de Bloeme, Christiaan M, Uner, Ogul E., Uner, O.E., Castelijns, J.A., Cardoen, L., Galluzzi, P., Moll, A.C., Jansen, R.W., Brisse, H.J., Dorsman, J., de Jong, Y., de Graaf, P., Roohollahi, K., Grossniklaus, H., Maeder, P., Sirin, S., de Bloeme, C.M., van der Valk, P., Hubbard, G.B., de Jong, M.C., Göricke, S.   +65 more
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The retinoblastoma protein modulates Tbx2 functional specificity [PDF]

, 2010
Tbx2 is a member of a large family of transcription factors defined by homology to the T-box DNA-binding domain. Tbx2 plays a key role in embryonic development, and in cancer through its capacity to suppress senescence and promote invasiveness.
Colin R. Goding, Heather M. Shaw, Sascha Ott, Keith W. Vance, Mercedes Rodriguez, Rodriguez, Mercedes, Goding, Colin R., Ott, Sascha, Shaw, Heather M., Vance, Keith W.   +9 more
core   +1 more source

Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining. [PDF]

, 2015
Deficiencies in DNA double-strand break (DSB) repair lead to genetic instability, a recognized cause of cancer initiation and evolution. We report that the retinoblastoma tumor suppressor protein (RB1) is required for DNA DSB repair by canonical non ...
Spanswick, VJ, Maciej T. Luczynski, Cook, R, Hartley, JA, Paul H. Huang, Victoria J. Spanswick, John A. Hartley, Luczynski, MT, Rieger, S, Mittnacht, S, Moquet, J, Huang, PH, Kai Rothkamm, Jayne Moquet, Zoumpoulidou, G, Georgia Zoumpoulidou, Simone Rieger, Sibylle Mittnacht, Rothkamm, K, Rebecca Cook   +19 more
core   +1 more source

Guidelines for imaging retinoblastoma: imaging principles and MRI standardization [PDF]

, 2011
Retinoblastoma is the most common intraocular tumor in children. The diagnosis is usually established by the ophthalmologist on the basis of fundoscopy and US.
Sophia Göricke, Rodjan, F., Philippe Maeder, Jonas A. Castelijns, de Graaf, P., Maeder, P., Paolo Galluzzi, Pim de Graaf, Castelijns, J.A., Hervé J. Brisse, Galluzzi, P., null null, Firazia Rodjan, Brisse, H.J., Galluzzi, Paolo, Maeder, Philippe, Brisse, Hervé J., de Graaf, Pim, Göricke, Sophia, Castelijns, Jonas A., Rodjan, Firazia, Göricke, S.   +21 more
core   +1 more source

Optic nerve thickening on high-spatial-resolution MRI predicts early-stage postlaminar optic nerve invasion in retinoblastoma [PDF]

, 2023
To assess the diagnostic accuracy of nerve thickening on MRI to predict early-stage postlaminar optic nerve invasion (PLONI) in retinoblastoma. Furthermore, this study aimed to incorporate measurements into a multiparametric model for radiological ...
Koob, M., Grauwels, STL, de Graaf, P., Maeder, P., Sirin, S., Cardoen, L., de Bloeme, C.M., Galluzzi, P., Moll, A.C., van Elst, S., Ketteler, P., van der Valk, P., Jansen, R.W., Brisse, H.J., de Jong, M.C., Göricke, S., Koob, Mériam, Brisse, Hervé J; https://orcid.org/, Ketteler, Petra, Jansen, Robin W; https://orcid.org/, Moll, Annette C; https://orcid.org/, de Graaf, Pim; https://orcid.org/, Cardoen, Liesbeth; https://orcid.org/, Grauwels, Steven T L, Sirin, Selma; https://orcid.org/, de Jong, Marcus C; https://orcid.org/, van Elst, Sabien; https://orcid.org/, Galluzzi, Paolo; https://orcid.org/, European Retinoblastoma Imaging Collaboration, Maeder, Philippe; https://orcid.org/, de Bloeme, Christiaan M; https://orcid.org/, Göricke, Sophia, van der Valk, Paul   +32 more
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Influence of retinoblastoma-related gene silencing on the initiation of DNA replication by African cassava mosaic virus Rep in cells of mature leaves in Nicotiana benthamiana plants [PDF]

, 2011
Background Geminiviruses mainly infect terminally differentiated tissues and cells in plants. They need to reprogramme host cellular machinery for DNA replication.
Yule Liu, Bruce, Gareth, Bruce Gareth, Liu, Yule, Liu Yule, Gareth Bruce, Nongnong Shi, Gu, Mei, Hong, Yiguo, Shi Nongnong, Yiguo Hong, Gu Mei, Shi, Nongnong, Hong Yiguo, Mei Gu   +14 more
core   +1 more source

RBBP7 (retinoblastoma binding protein 7) [PDF]

, 2010
Review on RBBP7 (retinoblastoma binding protein 7), with data on DNA, on the protein encoded, and where the gene is ...
Sinha, N, R Tamuli, Tamuli, R, N Sinha
core   +1 more source

RBBP8 (retinoblastoma binding protein 8) [PDF]

, 2009
Review on RBBP8 (retinoblastoma binding protein 8), with data on DNA, on the protein encoded, and where the gene is ...
Chinnadurai, G, Subramanian, T, Vijayalingam, S   +2 more
core   +1 more source