Results 11 to 20 of about 223,790 (352)
Unexpected evolutionary proximity of eukaryotic and cyanobacterial enzymes responsible for biosynthesis of retinoic acid and its oxidation [PDF]
, 2014 Biosynthesis of retinoic acid from retinaldehyde (retinal) is catalysed by an aldehyde dehydrogenase (ALDH) and its oxidation by cytochrome P450 enzymes (CYPs).
Gallagher, Connor +4 more
core +1 more source
International Journal of Applied and Basic Medical Research, 2017 Isotretinoin is a retinoid which is derived from Vitamin A. It is indicated for severe cystic acne treatment, but it has been classified as teratogenic. A wide spectrum of birth defects including craniofacial, heart, and nervous system malformations have been described with prenatal exposure to this drug.
Mondal, Dipankar +2 more
openaire +3 more sources
Journal of Lipid Research, 1985 An assay based on negative ion chemical ionization mass spectrometry has been developed to quantify retinoic acid in plasma or serum. The lower limit of detection is 75 pg (240 fmol); normal values of retinoic acid can be determined on as little as 40 ...
J L Napoli +4 more
doaj +1 more source
Proliferation versus Differentiation: Redefining Retinoic Acids Role. [PDF]
, 2018 Retinoic acid is commonly used in culture to differentiate stem cells into neurons and has established neural differentiation functions in vivo in developing and adult organisms. In this issue of Stem Cell Reports, Mishra et al.
Mosher, Kira, SCHAFFER, David
core +1 more source
CRABP proteins – relatives or homonyms?
Успехи молекулярной онкологии, 2015 Retinoic acid being the most active metabolite of vitamin A (retinol) regulates the wide spectrum of physiological processes including embryonic development, development of immune response, hematopoiesis, glucose and lipids metabolism, etc. Retinoic acid
E. M. Tchevkina, I. A. Favorskaya
doaj +1 more source
Fee Arrangements and Fee Shifting: Lessons From the Experience in Ontario [PDF]
, 1984 About one-third of oestrogen receptor alpha-positive breast cancer patients treated with tamoxifen relapse. Here we identify the nuclear receptor retinoic acid receptor alpha as a marker of tamoxifen resistance. Using quantitative mass spectrometry-based
Forshed, Jenny +17 more
core +3 more sources
Haematologica, 2019 Fatty acid oxidation dependency of leukemia cells has been documented in recent studies. Pharmacologic inhibition of fatty acid oxidation, thereby, displays significant effects in suppressing leukemia.
Ying Lu +9 more
doaj +1 more source
Retinoic acid is a potential dorsalising signal in the late embryonic chick hindbrain [PDF]
, 2007 Background: Human retinoic acid teratogenesis results in malformations of dorsally derived hindbrain structures such as the cerebellum, noradrenergic hindbrain neurons and the precerebellar system.
Maden, M +4 more
core +2 more sources
Journal of Lipid Research, 1990 Human plasma was analyzed by high performance liquid chromatography for the presence of retinoic acid and 4-oxoretinoic acid isomers. Peaks that coeluted with the reference compounds all-trans-retinoic acid, 13-cis-retinoic acid, and 13-cis-4-oxoretinoic
C Eckhoff, H Nau
doaj +1 more source
Effects of diet and strain on mouse serum and tissue retinoid concentrations. [PDF]
PLoS ONE, 2014 The relationship between dietary vitamin A and all-trans-retinoic acid levels in serum and tissues had not been quantified. We determined the impact of dietary vitamin A on retinoid levels in serum, liver, kidney, testis, and epididymal white adipose of ...
Kristin M Obrochta +2 more
doaj +1 more source