Results 11 to 20 of about 5,117,644 (334)
Retinoids regulate the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells. [PDF]
PLoS ONE, 2012 The retinoids, the natural or synthetic derivatives of Vitamin A (retinol), are essential for the normal development of prostate and have been shown to modulate prostate cancer progression in vivo as well as to modulate growth of several prostate cancer ...
Linda Kelsey +4 more
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Microbial Production of Bioactive Retinoic Acid Using Metabolically Engineered Escherichia coli
Microorganisms, 2021 Microbial production of bioactive retinoids, including retinol and retinyl esters, has been successfully reported. Previously, there are no reports on the microbial biosynthesis of retinoic acid.
Minjae Han, Pyung Cheon Lee
doaj +1 more source
Journal of Materials Science: Materials in Medicine, 2021 Despite recent advances in the treatment of human colon cancer, the chemotherapeutic efficacy against colon cancer is still unsatisfactory. The complexity in colorectal cancer treatment leads to new research in combination therapy to overcome multidrug ...
Narayan Ture +2 more
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Frontiers in Cell and Developmental Biology, 2022 Neuroblastoma is a pediatric tumour that accounts for more than 15% of cancer-related deaths in children. High-risk tumours are often difficult to treat, and patients’ survival chances are less than 50%. Retinoic acid treatment is part of the maintenance
Roshna Lawrence Gomez +9 more
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CRABP proteins – relatives or homonyms?
Успехи молекулярной онкологии, 2015 Retinoic acid being the most active metabolite of vitamin A (retinol) regulates the wide spectrum of physiological processes including embryonic development, development of immune response, hematopoiesis, glucose and lipids metabolism, etc. Retinoic acid
E. M. Tchevkina, I. A. Favorskaya
doaj +1 more source
Journal of Experimental Medicine, 2007 Foxp3+ regulatory T (T reg) cells play a key role in controlling immune pathological re actions. Many develop their regulatory activity in the thymus, but there is also evidence for development of Foxp3+ T reg cells from naive precursors in the periphery.
J. Coombes +6 more
semanticscholar +1 more source
Haematologica, 2019 Fatty acid oxidation dependency of leukemia cells has been documented in recent studies. Pharmacologic inhibition of fatty acid oxidation, thereby, displays significant effects in suppressing leukemia.
Ying Lu +9 more
doaj +1 more source
Binding of 9-cis-retinoic acid and all-trans-retinoic acid to retinoic acid receptors alpha, beta, and gamma. Retinoic acid receptor gamma binds all-trans-retinoic acid preferentially over 9-cis-retinoic acid [PDF]
Journal of Biological Chemistry, 1994 Both 9-cis-retinoic acid (RA) and all-trans-RA (t-RA) compete for [3H]9-cis-RA binding to RA receptors (RAR alpha, beta, and gamma) in nucleosol fractions from transiently transfected COS-1 cells with IC50 values of approximately 12 and 5 nM, respectively.
Joseph F. Grippo +5 more
openaire +2 more sources
Antiepileptogenic Effect of Retinoic Acid
Current Neuropharmacology, 2021 Retinoic acid, a metabolite of vitamin A, acts through either genomic or nongenomic actions. The genomic action of retinoids exerts effects on gene transcription through interaction with retinoid receptors such as retinoic acid receptors (RARα, β, and γ) and retinoid X receptors (RXRα, β, and γ) that are primarily concentrated in the amygdala, pre ...
Moisés Rubio-Osornio +4 more
openaire +4 more sources
Advances in Nutrition, 2019 Vitamin A is a fat-soluble essential nutrient obtained from plant- and animal-based sources that has roles in growth, vision, and metabolism. Vitamin A circulates mainly as retinol bound to retinol-binding protein 4 (RBP4), and is delivered to tissues ...
T. Olsen, R. Blomhoff
semanticscholar +1 more source