Results 11 to 20 of about 2,616,742 (302)

FGF and retinoic acid activity gradients control the timing of neural crest cell emigration in the trunk [PDF]

, 2011
Coordination between functionally related adjacent tissues is essential during development. For example, formation of trunk neural crest cells (NCCs) is highly influenced by the adjacent mesoderm, but the molecular mechanism involved is not well ...
Quiroga, Alejandra C, Kate G. Storey, Barbas, Julio A., Storey, Kate G, Morales, Aixa V., Alejandra C. Quiroga, Storey, Kate G., Das, R. M., Quiroga, Alejandra C., Barbas, Julio A, Aixa V. Morales, Raman M. Das, Das, Raman M., Morales, Aixa V, Olivera-Martinez, Isabel, Ruth Diez del Corral, Patricia L. Martínez-Morales, Julio A. Barbas, Martinez-Morales, Patricia L., Olivera-Martínez, I., Isabel Olivera-Martínez, Martínez-Morales, Patricia L, Diez del Corral, Ruth, Das, Raman M; id_orcid   +23 more
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Pathogenesis of retinoic acid-induced spina bifida in rat embryos [PDF]

, 2008
In a previous study, we showed that the intrauterine exposure of rat embryos to retinoic acid (RA) in the organogenesis period (8-11 days of gestation) induced various malformations according to the dose and timing of RA administration.
コニシ, ヒロヨシ, 小西, 啓悦, 1430, Konishi, Hiroyoshi   +3 more
core   +1 more source

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes. [PDF]

, 1996
1,25 (OH)(2) Vitamin D-3 (VD3) and retinoic acid (RA) function as ligands for nuclear receptors which regulate transcription, Though the cardiovascular system is not thought to represent a classical target for these ligands, it is clear that both cardiac
Gardner, D. G., J Wu, Garami, Miklós, Cheng, T., T Cheng, Wu, J., M Garami, D G Gardner   +7 more
core   +1 more source

Identification and quantitation of all-trans- and 13-cis-retinoic acid and 13-cis-4-oxoretinoic acid in human plasma.

Journal of Lipid Research, 1990
Human plasma was analyzed by high performance liquid chromatography for the presence of retinoic acid and 4-oxoretinoic acid isomers. Peaks that coeluted with the reference compounds all-trans-retinoic acid, 13-cis-retinoic acid, and 13-cis-4-oxoretinoic
C Eckhoff, H Nau
doaj   +1 more source

Effects of diet and strain on mouse serum and tissue retinoid concentrations. [PDF]

PLoS ONE, 2014
The relationship between dietary vitamin A and all-trans-retinoic acid levels in serum and tissues had not been quantified. We determined the impact of dietary vitamin A on retinoid levels in serum, liver, kidney, testis, and epididymal white adipose of ...
Kristin M Obrochta, Maureen A Kane, Joseph L Napoli   +2 more
doaj   +1 more source

Accumulation of hypoxia-inducible factor-1α protein and its role in the differentiation of myeloid leukemic cells induced by all-trans retinoic acid

Haematologica, 2008
Background The clinical activities of all-trans retinoic acid in the treatment of acute promyelocytic leukemia, a unique subtype of acute myeloid leukemia, have triggered extensive studies aimed at defining the mechanisms by which this compound induces ...
Jing Zhang, Li-Ping Song, Ying Huang, Qian Zhao, Ke-Wen Zhao, Guo-Qiang Chen   +5 more
doaj   +1 more source

TRAF inhibition drives cancer cell apoptosis and improves retinoic acid sensitivity in multiple cancers models

Discover Oncology, 2023
TNF receptor-associated factors (TRAFs) are signaling adaptor proteins that play a crucial role in regulating cellular receptors’ signaling transduction to downstream pathways and exert multifaceted roles in regulating signaling pathways, cell survival ...
Kun Zhong, Xiaojun Liu, Weihua Ding, Lizhong Peng, Xuhui Zeng, Yayun Gu   +5 more
doaj   +1 more source

Targeting the acute promyelocytic leukemia-associated fusion proteins PML/RARα and PLZF/RARα with interfering peptides [PDF]

, 2012
In acute promyelocytic leukemia (APL), hematopoietic differentiation is blocked and immature blasts accumulate in the bone marrow and blood. APL is associated with chromosomal aberrations, including t(15;17) and t(11;17).
Sabine Beez (123610), Beez, Sabine, Philipp Demmer, Elena Puccetti (66633), Philipp Demmer (123611), Puccetti, Elena, Elena Puccetti, Sabine Beez, Demmer, Philipp   +8 more
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Retinoic acid and microRNA

, 2020
Retinoic acid (RA), the biologically active metabolite of vitamin A, regulates a vast spectrum of biological processes, such as cell differentiation, proliferation, apoptosis, and morphogenesis. microRNAs (miRNAs) play a crucial role in regulating gene expression by binding to messenger RNA (mRNA) which leads to mRNA degradation and/or translational ...
Lijun, Wang, Atharva Piyush, Rohatgi, Yu-Jui Yvonne, Wan   +2 more
openaire   +3 more sources

The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer [PDF]

, 2014
Peer ...
Petronella Johansson, Johansson, Petronella, Gordon T Brown, Gordon T. Brown (532127), Beatriz Gimenez Cash, Beatriz Gimenez Cash (532128), Ayham Alnabulsi (532130), Graeme I. Murray (195455), Daniela Blihoghe, Cash, Beatriz Giminez, Alnabulsi, Ayham, Daniela Blihoghe (472704), Brown, Gordon T, Graeme I Murray, Ayham Alnabulsi, Petronella Johansson (532129), Blihoghe, Daniela, Murray, Graeme I   +17 more
core   +2 more sources