Results 31 to 40 of about 5,117,644 (334)
Detection and mode of action of retinoids on ovarian development in the mud crab, Scylla serrata
International Journal of Aquatic Biology, 2019 In the current study, the retinoic acid isomers such as 9-cis retinoic acid and all-trans retinoic acid were detected in the mature ovaries of mud crabs, Scylla serrata using HPLC analysis.
Kaduru Venkaiah +2 more
doaj +1 more source
Novel retinoic acid, 9-cis retinoic acid, in combination with all-trans retinoic acid is an effective inducer of differentiation of retinoic acid-resistant HL-60 cells [PDF]
Blood, 1994 Recent studies have shown that a high proportion of patients with acute promyelocytic leukemia (APL) achieve complete remission after treatment with all-trans retinoic acid (RA). Nevertheless, despite an initial good response, most patients that received continuous treatment with all-trans RA relapse and develop RA-resistant disease.
Hideaki Nakajima +8 more
openaire +4 more sources
Maternal smoking and the retinoid pathway in the developing lung
Respiratory Research, 2012 Background Maternal smoking is a risk factor for pediatric lung disease, including asthma. Animal models suggest that maternal smoking causes defective alveolarization in the offspring.
Manoli Sara E +7 more
doaj +1 more source
Potential Therapeutic Effect of All-Trans Retinoic Acid on Atherosclerosis
Biomolecules, 2022 Atherosclerosis is a major risk factor for myocardial infarction and ischemic stroke, which are the leading cause of death worldwide. All-trans retinoic acid (ATRA) is a natural derivative of essential vitamin A.
Qile Deng, Jixiang Chen
doaj +1 more source
The Roles of Retinoic Acid and Retinoic Acid Receptors in Inducing Epigenetic Changes [PDF]
, 2014 Epigenetics is "the branch of biology which studies the causal interactions between genes and their products which bring the phenotype into being" as defined by Conrad Waddington in 1942 in a discussion of the mechanisms of cell differentiation.
Alison M. Urvalek +2 more
openaire +3 more sources
SnapShot: Retinoic Acid Signaling
Cell, 2011 Retinoic acid (RA), a lipid soluble signaling molecule derived from vitamin A (retinol), regulates diverse biological processes, including cellular proliferation, differentiation, and apoptosis, throughout embryonic development. RA controls the expression of genes involved in patterning and morphogenesis during organogenesis.
Gregg Duester, Sandeep Kumar
openaire +3 more sources
Retinoic Acid as a Modulator of T Cell Immunity
Nutrients, 2016 Vitamin A, a generic designation for an array of organic molecules that includes retinal, retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including the proper functioning of the visual system, maintenance of cell ...
M. Bono +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source