Results 71 to 80 of about 223,790 (352)

Induction of lysosomal phospholipase A2 through the retinoid X receptor in THP-1 cells

open access: yesJournal of Lipid Research, 2004
An acidic phospholipase A2 (LPLA2) was recently purified and cloned. THP-1 cells were used to characterize the gene induction of LPLA2. THP-1 cells were stimulated with several differentiation agents.
Akira Abe   +3 more
doaj   +1 more source

SnapShot: Retinoic Acid Signaling

open access: yesCell, 2011
Retinoic acid (RA), a lipid soluble signaling molecule derived from vitamin A (retinol), regulates diverse biological processes, including cellular proliferation, differentiation, and apoptosis, throughout embryonic development. RA controls the expression of genes involved in patterning and morphogenesis during organogenesis.
Kumar, Sandeep, Duester, Gregg
openaire   +2 more sources

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

open access: yesAdvanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han   +9 more
wiley   +1 more source

Retinoic acid ortho-hydroxy aniline amide promotes neurotrophin mediated cell growth and proliferation in nerve cells

open access: yesBangladesh Journal of Pharmacology, 2015
In the present study, effect of retinoic acid ortho-hydroxy aniline amide (RAA), an analog of retinoic acid (RA) was investigated on neurotrophin mediated cell growth and proliferation in hippocampus-derived stem cell clones.
Zhi-Gang Wang   +4 more
doaj  

Antivirulence activities of retinoic acids against Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2023
Multidrug-resistant bacteria such as Staphylococcus aureus constitute a global health problem. Gram-positive S. aureus secretes various toxins associated with its pathogenesis, and its biofilm formation plays an important role in antibiotic tolerance and
Inji Park   +4 more
doaj   +1 more source

The effect of all-trans retinoic acid on the migration of avian neural crest cells in vitro an in vivo [PDF]

open access: yes, 2007
Student Number : 9502128Y - MSc dissertation - School of Anatomical Sciences - Faculty of ScienceRetinoic acid, the active metabolite of Vitamin A is known to play a major role in embryonic growth and differentiation during development.
Tshabalala, Vincent Abie Thabiso
core  

Retinoic acid and microRNA

open access: yes, 2020
Retinoic acid (RA), the biologically active metabolite of vitamin A, regulates a vast spectrum of biological processes, such as cell differentiation, proliferation, apoptosis, and morphogenesis. microRNAs (miRNAs) play a crucial role in regulating gene expression by binding to messenger RNA (mRNA) which leads to mRNA degradation and/or translational ...
Lijun, Wang   +2 more
openaire   +3 more sources

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Effect of caffeine and retinoic acid on skeleton of mice embryos

open access: yesJournal of Basic and Applied Zoology, 2016
The present study was conducted to evaluate the effect of caffeine and retinoic acid either separately or in combination on the skeleton of the developing embryos of mice.
Fakhr El-Din M. Lashein   +2 more
doaj   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

open access: yesAdvanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li   +19 more
wiley   +1 more source

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