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Expression and Distribution Pattern of Retinoic Acid Receptors in the Nasal Mucosa [PDF]
Journal of Rhinology, 2022 Background and Objectives Retinoids are naturally occurring vitamin A derivatives that regulate cellular processes and metabolism. In particular, retinoids play a key role in cellular proliferation by binding to retinoic acid receptors (RAR)-alpha, beta,
Jiwon Kwak +4 more
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Therapeutic Advances in Hematology, 2021 Some subtypes of acute myeloid leukemia (AML) share morphologic, immunophenotypic, and clinical features of acute promyelocytic leukemia (APL), but lack a PML–RARA (promyelocytic leukemia–retinoic acid receptor alpha) fusion gene.
Xiaoyan Han +7 more
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Frontiers in Oncology, 2023 Acute promyelocytic leukemia (APL) is a special subtype of acute myeloid leukemia (AML), 95% patients have PML-RARA fusion gene as a result of a reciprocal chromosomal translocation t(15;17)(q22; q21). The retinoic acid receptors (RARs) belong to nuclear
Wenjing Ding +13 more
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Thyroid hormone regulation of gene expression in primary cerebrocortical cells: role of thyroid hormone receptor subtypes and interactions with retinoic acid and glucocorticoids. [PDF]
PLoS ONE, 2014 The effects of thyroid hormone on brain development and function are largely mediated by the binding of 3,5,3'-triiodo-L-thyronine (T3) to its nuclear receptors (TR) to regulate positively or negatively gene expression.
Pilar Gil-Ibáñez +2 more
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Dual effects of 9-cis retinoic acid on ACTH-dependent hyperplastic adrenal tissues
Scientific Reports, 2021 Retinoids play a pivotal role in adrenal development and differentiation. Recent clinical trials revealed therapeutic potential of both all-trans and 9-cis retinoic acid in patients with cortisol excess due to a pituitary ACTH-secreting adenoma and ...
Francesca Pecori Giraldi +4 more
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Frontiers in Oncology, 2022 Some forms of acute myelogenous leukemia (AML) share typical morphological and immunophenotypic features of acute promyelocytic leukemia (APL) but are negative for promyelocytic leukemia-retinoic acid receptor alpha (PML-RARA) fusion.
Mingyan Jiang +9 more
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Acute Myelogenous Leukemia without Maturation with a Retinoic Alpha-Receptor Deletion: A Case Report
Case Reports in Oncology, 2014 Acute promyelocytic leukemia (APL) is characterized by a t(15;17) which fuses the 17q retinoic acid alpha-receptor sequence to the 15q PML gene sequence.
Christopher Trosclair +4 more
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Journal of Lipid Research, 1992 In this study, we examined effects of retinol deficiency and three retinoids, all-trans-retinoic acid, 13-cis-retinoic acid, and etretin, the aromatic derivative of retinoic acid on nuclear retinoic acid receptor isoforms alpha, beta, and gamma mRNA in ...
Riaz-ul-Haq, F Chytil
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Retinoic Acid Receptor β Expression in Oral Precancer Progression
International Dental Journal, 2023 Aim or Purpose: The burden of Oral Squamous Cell Carcinoma (OSCC) is huge because of the permanent impairment, high mortality and associated high cost of treatment. OSCC is often preceded by oral pre-cancer lesions/conditions (PMDs).
Prof Shaleen Chandra +2 more
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Induction of lysosomal phospholipase A2 through the retinoid X receptor in THP-1 cells
Journal of Lipid Research, 2004 An acidic phospholipase A2 (LPLA2) was recently purified and cloned. THP-1 cells were used to characterize the gene induction of LPLA2. THP-1 cells were stimulated with several differentiation agents.
Akira Abe +3 more
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