Dimerization with Retinoid X Receptors and Phosphorylation Modulate the Retinoic Acid-induced Degradation of Retinoic Acid Receptors α and γ through the Ubiquitin-Proteasome Pathway [PDF]
Eliezer Kopf +5 more
openalex +1 more source
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry +27 more
wiley +1 more source
ALDH1A1 promotes PARP inhibitor resistance by enhancing retinoic acid receptor-mediated DNA polymerase θ expression. [PDF]
Lavudi K +15 more
europepmc +1 more source
Expression of retinoic acid receptor in human colorectal cancer
Jiafeng Fang +5 more
openalex +2 more sources
Prioritising research on endocrine disruption in the marine environment: a global perspective
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto +23 more
wiley +1 more source
Exploring the interactions of antihistamine with retinoic acid receptor beta (RARB) by molecular dynamics simulations and genome-wide meta-analysis. [PDF]
Kim MJ +3 more
europepmc +1 more source
All-trans-retinoic acid modulates glycolysis via H19 and telomerase: the role of mir-let-7a in estrogen receptor-positive breast cancer cells [PDF]
Rita El Habre +3 more
openalex +1 more source
Feedback Inhibition of the Retinaldehyde Dehydrogenase GeneALDH1 by Retinoic Acid through Retinoic Acid Receptor α and CCAAT/Enhancer-binding Protein β [PDF]
Guillermo Elizondo +3 more
openalex +1 more source
FBMTG‐APL2017: First prospective multicenter trial evaluating frontline ATRA‐ATO therapy for newly diagnosed APL in Japan, encompassing both low–intermediate (n = 65) and high‐risk (n = 16) patients. Excellent outcomes (95% CR, 94% 3‐year DFS) with comparable efficacy between risk groups (DFS: 97% vs.
Ken Takase +14 more
wiley +1 more source
Retinoic acid receptor β deletion in podocytes causes kidney and liver dysfunction, modeling nephrotic syndrome. [PDF]
Chi Y +8 more
europepmc +1 more source

