Results 191 to 200 of about 86,354 (308)

From Discovery to Clinical Trial: YCT-529, an Oral NonHormonal Male Contraceptive Targeting the Retinoic Acid Receptor Alpha. [PDF]

J Med Chem
Shi R, Al Noman MA, Mannowetz N, Cheryala N, Haque E, Maitra S, Naqvi T, Chung SSW, Bakshi A, Hawkinson JE, Wong HL, Wolgemuth DJ, Georg GI.   +12 more
europepmc   +1 more source

A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment. [PDF]

Sci Rep, 2023
Wei CH, Huang L, Kreh B, Liu X, Tyutyunyk-Massey L, Kawakami M, Chen Z, Shi M, Kozlov S, Chan KC, Andresson T, Carrington M, Vuligonda V, Sanders ME, Horowitz A, Hwu P, Peng W, Dmitrovsky E, Liu X.   +18 more
europepmc   +1 more source

Retinoic acid receptor assembly dynamics governs dual functions in cochlear organogenesis. [PDF]

Proc Natl Acad Sci U S A
Chakraborty S, Wang S, Ruhala J, Mehling B, Liu J, Waldhaus J.   +5 more
europepmc   +1 more source

Functional analysis of the HOX11 target genes ALDH1A1 and FHL1

, 2004
HOX11 is a developmental regulator that plays a crucial role in the normal development of the spleen and is also aberrantly activated by the t(10;14)(q24;q11) and variant t(7;10)(q35;q24) translocations in a subset of T-cell acute lymphoblastic ...
Rice, Kim
core  

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury

Cell Proliferation, EarlyView.
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu, Zhenan Zhang, Weifeng Hao, Chunyan Zhou, Deqin Yang   +4 more
wiley   +1 more source

Retinoic acid receptor-related orphan receptor α regulates bystander activation of memory CD8⁺ T cells. [PDF]

Front Immunol
Cai Z, Kozai M, Mita H, Takeuchi H, Mizuno S, Matsuo K, Takada K.   +6 more
europepmc   +1 more source

Investigation of selective retinoic acid receptor alpha antagonist ER-50891 and related analogs for male contraception. [PDF]

Arch Pharm (Weinheim), 2023
Kyzer JL, Noman MAA, Cuellar RAD, Chung SSW, Maitra S, Naqvi T, Hawkinson JE, Wolgemuth DJ, Georg GI.   +8 more
europepmc   +1 more source

Bridging Kidney Organoid Innovation and Regenerative Medicine: Current Advances and Future Directions

Cell Proliferation, EarlyView.
This review outlines kidney organoid differentiation strategies, key developmental mechanisms, and engineering and multi‐omics approaches driving their progress toward regenerative medicine. ABSTRACT Chronic kidney disease (CKD) has emerged as a critical public health challenge worldwide, and organ donor shortages underscore the urgent need for ...
Bohong Guo, Jingyuan Zhang, Xuening Fang, Yangyang Liu, Yueyang Deng, Yuxin Xue, Zhengxi Wang, Xiaotao Dong, Mengqi Jia, Xiaodong Li   +9 more
wiley   +1 more source

Redefining retinoic acid receptor expression in zebrafish embryos using Hybridization Chain Reaction. [PDF]

Differentiation
Gray R, Lovely CB.
europepmc   +1 more source

Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β (RARβ) Gene in Hepatocytes. [PDF]

Int J Mol Sci, 2023
Zolfaghari R, Bonzo JA, Gonzalez FJ, Ross AC.   +3 more
europepmc   +1 more source