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The Role of Specific Retinoid Receptors in Sebocyte Growth and Differentiation in Culture11Presented in part at the 1999 Annual Meeting of the Pediatric Academic Societies, San Francisco, CA, May 1–4 (Pediat Res 45 (Part 2): 55A [Abst 313] 1999) [PDF]
, 2000 Retinoic acid derivatives (retinoids) exert their pleiotropic effects on cell development through specific nuclear receptors, the retinoic acid receptors and retinoid X receptors.
Ciletti, Nancy +4 more
core +1 more source
Neural Regeneration Research, 2019 All retinoids, which can be natural and synthetic, are chemically related to vitamin A. Both natural and synthetic retinoids use specific nuclear receptors such as retinoic acid receptors and retinoid X receptors to activate specific signaling pathways ...
Bhaskar C Das +2 more
doaj +1 more source
Nutrition & Metabolism, 2023 In the last century, vitamin A was identified that included the nutritional relevant vitamin A1 / provitamin A1, as well as the vitamin A2 pathway concept.
Torsten Bohn +4 more
doaj +1 more source
Differential effects of retinoic acid isomers on the expression of nuclear receptor co-regulators in neuroblastoma [PDF]
, 1999 Retinoic acid modulates growth and induces differentiation and apoptosis of neuroblastoma cells in vitro, with the all-trans and 9-cis isomers having different biological properties.
Annicchiarico-Petruzzelli, Margherita +7 more
core +1 more source
Antagonism between retinoic acid receptors. [PDF]
Molecular and Cellular Biology, 1991 In the developing mouse, retinoic acid receptors (RARs) beta and gamma 1 are expressed in characteristic spatiotemporal patterns which are correlated with different developmental fates of the respective tissues. Understanding the cues that regulate the expression of the various RARs may therefore provide insights into the process of tissue ...
Matthias Husmann +5 more
openaire +3 more sources
CRABP proteins – relatives or homonyms?
Успехи молекулярной онкологии, 2015 Retinoic acid being the most active metabolite of vitamin A (retinol) regulates the wide spectrum of physiological processes including embryonic development, development of immune response, hematopoiesis, glucose and lipids metabolism, etc. Retinoic acid
E. M. Tchevkina, I. A. Favorskaya
doaj +1 more source
Differential effects of steroids and retinoids on bovine myelopoiesis in vitro [PDF]
, 2004 Pregnancy and parturition are associated with physiological changes caused by steroid hormones. Alterations in number, maturity, and function of polymorphonuclear leukocytes observed in dairy cows at parturition suggest a common causative relationship ...
Burvenich, Christian +3 more
core +1 more source
A Retinoic Acid Receptor-Specific Element Controls the Retinoic Acid Receptor-β Promoter [PDF]
Molecular Endocrinology, 1990 The morphogen retinoic acid (RA) regulates gene transcription by interacting with specific nuclear receptors that recognize DNA sequences near responsive promoters. While much has recently been learned about the nuclear receptor proteins, little is known about the genes that are directly regulated by RA and their cis-acting response elements recognized
Magnus Pfahl +6 more
openaire +3 more sources
Role of vitamin A/retinoic acid in regulation of embryonic and adult hematopoiesis [PDF]
, 2017 Vitamin A is an essential micronutrient throughout life. Its physiologically active metabolite retinoic acid (RA), acting through nuclear retinoic acid receptors (RARs), is a potent regulator of patterning during embryonic development, as well as being ...
Adamo +23 more
core +4 more sources
Activation of Retinoic Acid Receptors by Dihydroretinoids [PDF]
Molecular Pharmacology, 2009 Vitamin A-derived metabolites act as ligands for nuclear receptors controlling the expression of a number of genes. Stereospecific saturation of the C(13)-C(14) double bond of all-trans-retinol by the enzyme, retinol saturase (RetSat), leads to the production of (R)-all-trans-13,14-dihydroretinol.
Alexander R Moise +8 more
semanticscholar +4 more sources